Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 5/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TYR | P14679 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL979606 | 0.83 | LIPG (0.40) | GPR35LIPGCYSLTR2CYSLTR1MAPT | |
| SCHEMBL586816 | 0.83 | LIPG (0.40) | GPR35LIPGCYSLTR2CYSLTR1MAPT | |
| SCHEMBL30544 | 0.83 | GPR35 (0.55) | GPR35LTB4RCYSLTR2CYSLTR1ALDH1A1 | |
| SCHEMBL28502292 | 0.82 | LIPG (0.39) | GPR35LTB4RLIPGCYSLTR2CYSLTR1 | |
| SCHEMBL28905105 | 0.82 | LIPG (0.39) | GPR35LTB4RLIPGCYSLTR2CYSLTR1 | |
| SCHEMBL28510615 | 0.82 | LIPG (0.39) | GPR35LTB4RLIPGCYSLTR2CYSLTR1 | |
| SCHEMBL28497574 | 0.82 | LIPG (0.39) | GPR35LTB4RLIPGCYSLTR2CYSLTR1 | |
| SCHEMBL17353545 | 0.81 | GPR35 (0.57) | GPR35LTB4RCYSLTR2CYSLTR1BID | |
| SCHEMBL4436638 | 0.81 | GPR35 (0.57) | GPR35LTB4RCYSLTR2CYSLTR1BID | |
| SCHEMBL8516407 | 0.81 | GPR35 (0.57) | GPR35LTB4RCYSLTR2CYSLTR1BID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090098047-A1 | BIOCONJUGATES OF METAL COMPLEXES OF NITROGEN-CONTAINING MACROCYCLIC LIGANDS | INOTEK PHARMACEUTICALS (NZ) | 2009-04-16 | — | — | US | claimed |
| US-20040131550-A1 | Bioconjugates of metal complexes of nitrogen-containing macrocyclic ligands | METAPHORE PHARMACEUTICALS, INC. | 2004-07-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040131550-A1 | Bioconjugates of metal complexes of nitrogen-containing macrocyclic ligands | RXFP3, RXFP1, RCN1 | GPR35 2209/4885LTB4R 1671/4885LIPG 4429/4885 |
| US-20090098047-A1 | BIOCONJUGATES OF METAL COMPLEXES OF NITROGEN-CONTAINING MACROCYCLIC LIGANDS | RXFP3, RXFP1, C3AR1 | GPR35 2525/4885LTB4R 1469/4885LIPG 4595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.