Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 5/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.35 |
| ▸ | TUBB | P07437 | 5/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.35 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.35 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.35 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4215108 | 0.92 | GRM7 (0.41) | GRM7IMPDH2TUBB4ATUBBTUBA3C | |
| SCHEMBL4223184 | 0.80 | ERN1 (0.41) | GRM7IMPDH2TUBB4ATUBBTUBA3C | |
| SCHEMBL1309464 | 0.74 | TUBB4A (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4036659 | 0.74 | ERN1 (0.41) | GRM7IMPDH2TUBB4ATUBBTUBA3C | |
| SCHEMBL1307850 | 0.72 | TUBB4A (0.44) | GRM7IMPDH2TUBB4ATUBBTUBA3C | |
| SCHEMBL1307770 | 0.72 | TUBB4A (0.55) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1307587 | 0.72 | TUBB4A (0.44) | GRM7IMPDH2TUBB4ATUBBTUBA3C | |
| SCHEMBL1308486 | 0.72 | TUBB4A (0.38) | GRM7IMPDH2TUBB4ATUBBTUBA3C | |
| SCHEMBL4040976 | 0.70 | TUBB4A (0.38) | GRM7IMPDH2TUBB4ATUBBTUBA3C | |
| SCHEMBL15225902 | 0.69 | ERN1 (0.43) | MAPTPIK3R1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066632-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | Chong Kun Dang Pharmaceutical Corp. (KR) | 2009-06-10 | — | — | EP | claimed |
| WO-2008038955-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2008-04-03 | — | — | WO | claimed |