Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 2/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4035120 | 0.76 | TUBB4A (0.49) | ALDH1A1KDM4ESMN1; SMN2MAPTHPGD | |
| SCHEMBL192940 | 0.70 | ALDH1A1 (0.51) | ALDH1A1KDM4ESMN1; SMN2MAPTHPGD | |
| SCHEMBL4538692 | 0.69 | GRM7 (0.37) | PIK3R1PIK3CAMAPT | |
| SCHEMBL1308192 | 0.69 | TUBB4A (0.38) | ERN1ALDH1A1MAPTHPGDFLT3 | |
| SCHEMBL13632104 | 0.68 | TUBB4A (0.43) | ERN1ALDH1A1MAPTHPGDEGLN1 | |
| SCHEMBL610633 | 0.68 | ERN1 (0.49) | ERN1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL15225811 | 0.65 | CYP2A6 (0.35) | ERN1ALDH1A1KDM4ECHEK1HPGD | |
| SCHEMBL1309464 | 0.65 | TUBB4A (0.64) | ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL4215108 | 0.63 | GRM7 (0.41) | PIK3R1PIK3CAMAPT | |
| SCHEMBL27972411 | 0.63 | LMNA (0.47) | ALDH1A1KDM4ESMN1; SMN2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066632-B1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | CHONG KUN DANG PHARM CORP (KR) | 2013-09-04 | — | — | EP | disclosed |