Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.45 |
| ▸ | TACR3 | P29371 | 1/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8038556 | 0.91 | PPARG (0.61) | PPARGHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL8038553 | 0.89 | PPARG (0.60) | PPARGHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL4537762 | 0.86 | PPARG (0.48) | PPARGHDAC1KDM4EALDH1A1GAA | |
| SCHEMBL4540765 | 0.86 | MEN1 (0.52) | PPARGHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL8028550 | 0.86 | PPARG (0.58) | PPARGTACR3KDM4EALDH1A1MAPT | |
| SCHEMBL8034344 | 0.86 | PPARG (0.54) | PPARGHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL8045581 | 0.85 | PPARG (0.50) | PPARGHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL4536851 | 0.84 | MAPT (0.54) | PPARGALDH1A1MAPT | |
| SCHEMBL8040416 | 0.84 | PPARG (0.58) | PPARG | |
| SCHEMBL8042117 | 0.83 | PPARG (0.59) | PPARGHDAC1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |