Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | PLEC | Q15149 | 1/20 | 0.46 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034344 | 0.93 | PPARG (0.54) | PPARGMAPTHDAC1KCNA5 | |
| SCHEMBL8032490 | 0.93 | PPARG (0.55) | PPARGMAPK1HDAC1GAA | |
| SCHEMBL4537211 | 0.92 | KCNK3 (0.50) | PPARGHDAC8MAPTHDAC1HDAC6 | |
| SCHEMBL8038740 | 0.90 | PPARG (0.57) | PPARGMAPK1GAA | |
| SCHEMBL4540765 | 0.89 | MEN1 (0.52) | PPARGHDAC8MAPTHDAC1HDAC6 | |
| SCHEMBL8034539 | 0.89 | PPARG (0.56) | PPARGHDAC8HDAC1HDAC6 | |
| SCHEMBL8034326 | 0.87 | PPARG (0.48) | PPARGHDAC8 | |
| SCHEMBL8040416 | 0.86 | PPARG (0.58) | PPARGKCNA5 | |
| SCHEMBL4538730 | 0.86 | PPARG (0.57) | PPARGMAPTHDAC1KDM4EALDH1A1 | |
| SCHEMBL4537201 | 0.85 | PPARG (0.57) | PPARGMAPTMAPK1HDAC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |