Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.63 |
| ▸ | ABL1 | P00519 | 1/20 | 0.63 |
| ▸ | PPARG | P37231 | 1/20 | 0.63 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.63 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.62 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.62 |
| ▸ | MAOB | P27338 | 9/20 | 0.49 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | HPD | P32754 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL94520 | 0.84 | NSD2 (0.54) | NSD2ABL1PPARGRIN1L3MBTL1 | |
| SCHEMBL6683297 | 0.82 | NSD2 (0.55) | NSD2ABL1PPARGRIN1L3MBTL1 | |
| SCHEMBL94569 | 0.81 | NSD2 (0.51) | NSD2ABL1PPARGRIN1L3MBTL1 | |
| SCHEMBL1003252 | 0.78 | NSD2 (0.55) | NSD2ABL1PPARGRIN1L3MBTL1 | |
| SCHEMBL136664 | 0.78 | NSD2 (1.00) | NSD2ABL1PPARGRIN1L3MBTL1 | |
| SCHEMBL14151016 | 0.76 | NSD2 (0.63) | NSD2ABL1PPARGRIN1L3MBTL1 | |
| SCHEMBL21580161 | 0.75 | SCN3A (0.53) | PARP15PARP10MAOBPARP14SCN3A | |
| SCHEMBL1003510 | 0.75 | NSD2 (0.71) | NSD2ABL1PPARGRIN1L3MBTL1 | |
| SCHEMBL3475457 | 0.73 | NSD2 (0.64) | NSD2ABL1PPARGRIN1L3MBTL1 | |
| SCHEMBL27904706 | 0.73 | NSD2 (0.88) | NSD2ABL1PPARGRIN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107466294-B | Indole derivatives | 吉瑞工厂 | 2020-01-17 | — | — | CN | disclosed |
| EP-3286193-A1 | INDOLE DERIVATIVES | Richter Gedeon Nyrt. (HU) | 2018-02-28 | — | — | EP | disclosed |
| WO-2016166684-A1 | INDOLE DERIVATIVES | RICHTER GEDEON NYRT. (HU) | 2016-10-20 | — | — | WO | disclosed |
| US-20090264426-A1 | Bicyclic aromatic substituted pyridone derivative | MSD K.K. (JP) | 2009-10-22 | — | — | US | disclosed |
| EP-1939194-A1 | BICYCLIC AROMATIC SUBSTITUTED PYRIDONE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-07-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264426-A1 | Bicyclic aromatic substituted pyridone derivative | PYCR1, CHRM1, MTR | NSD2 2048/4885ABL1 2355/4885PPARG 1639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.