SCHEMBL453983

SCHEMBL453983

CC([SiH3])=C(C)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.48
CES2 O00748 3/20 0.44
CES1 P23141 3/20 0.44
PTGS2 P35354 2/20 0.41
TSHR P16473 3/20 0.39
ALDH1A1 P00352 2/20 0.39
DAO P14920 1/20 0.39
NAPRT Q6XQN6 1/20 0.39
CYP19A1 P11511 2/20 0.37
MAPT P10636 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
LMNA P02545 1/20 0.37
MAPK1 P28482 1/20 0.37
HTT P42858 1/20 0.37
F2 P00734 1/20 0.36
F10 P00742 1/20 0.36
F12 P00748 1/20 0.36
F7 P08709 1/20 0.36
F3 P13726 1/20 0.36
PKM P14618 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3902058 0.82 ESR1 (0.56) ESR1CES2CES1PTGS2TSHR
SCHEMBL11844374 0.82 ESR1 (0.56) ESR1CES2CES1PTGS2TSHR
SCHEMBL1035354 0.82 ESR1 (0.56) ESR1CES2CES1PTGS2TSHR
SCHEMBL10871237 0.81 ESR1 (0.46) ESR1CES2CES1PTGS2TSHR
SCHEMBL23278527 0.79 ESR1 (0.61) ESR1CES2CES1PTGS2TSHR
SCHEMBL58000 0.77 ESR1 (0.52) ESR1CES2CES1PTGS2TSHR
SCHEMBL8676275 0.77 ESR1 (0.58) ESR1CES2CES1PTGS2TSHR
SCHEMBL6138842 0.77 ESR1 (0.52) ESR1CES2CES1PTGS2TSHR
SCHEMBL3797764 0.74 ESR1 (0.50) ESR1CES2CES1PTGS2TSHR
SCHEMBL3797762 0.74 ESR1 (0.50) ESR1CES2CES1PTGS2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 399 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116284623-A Method for preparing branched SBS by adopting micro-mixing continuous flow reactor 大连理工大学 2023-06-23 CN claimed
US-6184170-B1 COMBINING AT LEAST ONE METALLOCENE, AT LEAST ONE ACTIVATOR, AND AT LEAST ONE PROMOTER WHEREIN THE PROMOTER COMPRISES ALLYLBENZENE, VINYLTRIMETHYLSILANE, VINYLDIETHYLMETHYLSILANE, PHENYLMETHYLVINYLSILANE; POLYMERIZATION CATALYST EXXON CHEMICAL PATENTS, INC. 2001-02-06 US claimed
CN-116284623-A Method for preparing branched SBS by adopting micro-mixing continuous flow reactor 大连理工大学 2023-06-23 CN disclosed
EP-2915824-B1 METALLOCENE LIGANDS, METALLOCENE COMPOUNDS AND METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) 2022-05-25 EP disclosed
US-10392455-B2 Process for controlling the polymer composition of an ethylene copolymer obtained by a catalyst system comprising a transition metal catalyst component and a Ziegler catalyst component BASELL POLYOLEFINE GMBH (DE) 2019-08-27 US disclosed
CN-109153760-A Block copolymer for 10NM or less composition 得克萨斯大学体系董事会 2019-01-04 CN disclosed
EP-2220101-B1 TRANSITION METAL COMPOUNDS BASELL POLYOLEFINE GMBH (DE) 2018-09-19 EP disclosed
EP-1943281-B1 HYBRID CATALYST SYSTEMS SUPPORTED ON MAGNESIUM HALIDE BASELL POLYOLEFINE GMBH (DE) 2017-09-20 EP disclosed
CN-104364277-B Process for controlling the polymer composition of an ethylene copolymer obtained from a catalyst system comprising a transition metal catalyst component and a ziegler catalyst component 巴塞尔聚烯烃股份有限公司 2017-02-22 CN disclosed
EP-1824888-B1 MONOCYCLOPENTADIENYL COMPLEXES BASELL POLYOLEFINE GMBH (DE) 2017-01-18 EP disclosed
EP-2794691-B1 PROCESS FOR CONTROLLING THE POLYMER COMPOSITION OF AN ETHYLENE COPOLYMER OBTAINED BY A CATALYST SYSTEM COMPRISING A TRANSITION METAL CATALYST COMPONENT AND A ZIEGLER CATALYST COMPONENT BASELL POLYOLEFINE GMBH (DE) 2016-06-22 EP disclosed
WO-2001036497-A1 SUPPORTED ORGANOMETALLIC CATALYSTS AND THEIR USE IN OLEFIN POLYMERIZATION EXXON CHEMICAL PATENTS INC. (US) 2001-05-25 WO disclosed
WO-2001036499-A1 PREPARATION OF SUPPORTED POLYMERIZATION CATALYSTS EXXON CHEMICAL PATENTS INC. (US) 2001-05-25 WO disclosed
US-6184170-B1 COMBINING AT LEAST ONE METALLOCENE, AT LEAST ONE ACTIVATOR, AND AT LEAST ONE PROMOTER WHEREIN THE PROMOTER COMPRISES ALLYLBENZENE, VINYLTRIMETHYLSILANE, VINYLDIETHYLMETHYLSILANE, PHENYLMETHYLVINYLSILANE; POLYMERIZATION CATALYST EXXON CHEMICAL PATENTS, INC. 2001-02-06 US disclosed
US-6136742-A Metallocene catalyst systems EXXON CHEMICAL PATENTS, INC. (US) 2000-10-24 US disclosed
US-5264646-A Vinylation, benzocyclobutenes, polysiloxanes THE DOW CHEMICAL COMPANY (US) 1993-11-23 US disclosed
US-5243068-A Alkenylation with organic halides THE DOW CHEMICAL COMPANY (US) 1993-09-07 US disclosed
EP-0506314-A2 Process for preparing vinylically-unsaturated compounds THE DOW CHEMICAL COMPANY (US) 1992-09-30 EP disclosed
US-5138081-A Peroxidation of organophosphine or organoarsine impurities; chromatography THE DOW CHEMICAL COMPANY (US) 1992-08-11 US disclosed
US-5136069-A Reacting with halogenated organic compound in presence of palladium complex catalyst and inorganic hydrogen halide acceptor THE DOW CHEMICAL COMPANY (US) 1992-08-04 US disclosed