Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 3/20 | 0.42 |
| ▸ | CES1 | P23141 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | F12 | P00748 | 1/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | F3 | P13726 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5831030 | 0.81 | CES2 (0.44) | ESR1CES2CES1TSHRALDH1A1 | |
| SCHEMBL453983 | 0.81 | ESR1 (0.48) | ESR1CES2CES1PTGS2TSHR | |
| SCHEMBL1035354 | 0.80 | ESR1 (0.56) | ESR1CES2CES1PTGS2TSHR | |
| SCHEMBL3902058 | 0.80 | ESR1 (0.56) | ESR1CES2CES1PTGS2TSHR | |
| SCHEMBL11844374 | 0.80 | ESR1 (0.56) | ESR1CES2CES1PTGS2TSHR | |
| SCHEMBL23278527 | 0.77 | ESR1 (0.61) | ESR1CES2CES1PTGS2TSHR | |
| SCHEMBL15302398 | 0.77 | CES1 (0.41) | ESR1CES2CES1TSHRALDH1A1 | |
| SCHEMBL15302785 | 0.77 | CES2 (0.41) | ESR1CES2CES1TSHRALDH1A1 | |
| SCHEMBL16933865 | 0.76 | ESR1 (0.48) | ESR1CES2CES1PTGS2TSHR | |
| SCHEMBL58000 | 0.75 | ESR1 (0.52) | ESR1CES2CES1PTGS2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122059978-A | Synthesis method of diaryl compound containing silicon atom | 南京工业大学 | 2026-05-19 | — | — | CN | disclosed |
| EP-4150021-B1 | OPTICALLY TRANSPARENT 3D PRINTED POLYSILOXANE SCINTILLATORS | L LIVERMORE NAT SECURITY LLC (US) | 2025-04-16 | — | — | EP | disclosed |
| US-12195634-B2 | Optically transparent 3D printed polysiloxane scintillators | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2025-01-14 | — | — | US | disclosed |
| CN-118956271-A | Optical film containing prism layer and preparation method thereof | 南京贝迪新材料科技股份有限公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-115838379-A | Preparation method of methyl phenyl vinyl silanol | 嘉兴联合化学有限公司 | 2023-03-24 | — | — | CN | disclosed |
| EP-4150021-A1 | OPTICALLY TRANSPARENT 3D PRINTED POLYSILOXANE SCINTILLATORS | Lawrence Livermore National Security, LLC (US) | 2023-03-22 | — | — | EP | disclosed |
| WO-2021211954-A1 | OPTICALLY TRANSPARENT 3D PRINTED POLYSILOXANE SCINTILLATORS | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2021-10-21 | — | — | WO | disclosed |
| US-20210324217-A1 | OPTICALLY TRANSPARENT 3D PRINTED POLYSILOXANE SCINTILLATORS | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC. | 2021-10-21 | — | — | US | disclosed |
| EP-2620441-B1 | MODIFIED PRODUCT OF POLYHEDRAL STRUCTURE POLYSILOXANE, POLYHEDRAL STRUCTURE POLYSILOXANE COMPOSITION, CURED PRODUCT, AND OPTICAL SEMICONDUCTOR DEVICE | KANEKA CORP (JP) | 2018-10-31 | — | — | EP | disclosed |
| US-9698320-B2 | Modified product of polyhedral structure polysiloxane, polyhedral structure polysiloxane composition, cured product, and optical semiconductor device | KANEKA CORPORATION (JP) | 2017-07-04 | — | — | US | disclosed |
| US-20130237663-A1 | MODIFIED PRODUCT OF POLYHEDRAL STRUCTURE POLYSILOXANE, POLYHEDRAL STRUCTURE POLYSILOXANE COMPOSITION, CURED PRODUCT, AND OPTICAL SEMICONDUCTOR DEVICE | KANEKA CORPORATION (JP) | 2013-09-12 | — | — | US | disclosed |
| EP-2620441-A1 | MODIFIED PRODUCT OF POLYHEDRAL STRUCTURE POLYSILOXANE, POLYHEDRAL STRUCTURE POLYSILOXANE COMPOSITION, CURED PRODUCT, AND OPTICAL SEMICONDUCTOR DEVICE | Kaneka Corporation (JP) | 2013-07-31 | — | — | EP | disclosed |
| EP-0186452-A2 | Organosilicon compounds process for their production and pharmaceutical compositions thereof | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1986-07-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130237663-A1 | MODIFIED PRODUCT OF POLYHEDRAL STRUCTURE POLYSILOXANE, POLYHEDRAL STRUCTURE POLYSILOXANE COMPOSITION, CURED PRODUCT, AND OPTICAL SEMICONDUCTOR DEVICE | HSF1, PIEZO1, HSP90AA1 | ESR1 2021/4885CES2 3978/4885CES1 4673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.