SCHEMBL453986

SCHEMBL453986

CCOC(=O)CCNCCC[Si](OCC)(OCC)OCC

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 4/20 0.44
CYP1A2 P05177 2/20 0.41
GAA P10253 2/20 0.40
MGAM O43451 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
CYP3A4 P08684 1/20 0.37
CYP2C19 P33261 1/20 0.37
ALDH1A1 P00352 2/20 0.37
TOP2A P11388 1/20 0.37
KDM4E B2RXH2 1/20 0.36
HPGD P15428 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
POLB P06746 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4453227 0.89 TSHR (0.41) LTA4HALDH1A1SMN1; SMN2KMT2A
SCHEMBL30771773 0.87 LTA4H (0.44) LTA4HCYP1A2GAAMGAMSI
SCHEMBL31042785 0.86 LTA4H (0.43) LTA4HCYP1A2GAAMGAMSI
SCHEMBL31042732 0.86 LTA4H (0.43) LTA4HCYP1A2GAAMGAMSI
SCHEMBL27841154 0.86 LTA4H (0.40) LTA4HCYP1A2GAAALDH1A1
SCHEMBL17779431 0.86 LTA4H (0.37) LTA4HGAAALDH1A1TOP2A
SCHEMBL30968316 0.86 LTA4H (0.39) LTA4H
SCHEMBL15012198 0.85 GAA (0.45) LTA4HCYP1A2GAAMGAMSI
SCHEMBL11905395 0.84 PAOX (0.34) LTA4H
SCHEMBL11905306 0.83 PLA2G2A (0.37) LTA4HKDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4414272-A SILICA, EPOXIDE, SILANE COUPLER OR ORGANOTITANIUM COMPOUND TEIJIN LIMITED (JP) 1983-11-08 US claimed
EP-0048481-A2 Shaped polyester composite material having an activated surface thereof and process for producing the same TEIJIN LIMITED (JP) 1982-03-31 EP claimed
EP-4660271-A1 COMPOSITION CONTAINING LINEAR AMINOSILANE COMPOUND HAVING CARBOXYLIC ESTER GROUP AND CYCLIC SILAZANE COMPOUND HAVING CARBOXYLIC ESTER GROUP, AND METHOD FOR PRODUCING SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-12-10 EP disclosed
WO-2025109942-A1 MOLDED PRODUCT CONTAINING INORGANIC PARTICLES AND WATER SOLUBLE POLYSILOXANE COMPOUND HAVING AMINO GROUP, METHOD FOR PRODUCING SAME, AND INORGANIC PARTICLE DISPERSION LIQUID 信越化学工業株式会社 2025-05-30 WO disclosed
WO-2025109943-A1 SOLID WATER-SOLUBLE POLYSILOXANE COMPOUND HAVING AMINO ACID-CONTAINING GROUP, AND METHOD FOR PRODUCING SAME 信越化学工業株式会社 2025-05-30 WO disclosed
WO-2024161857-A1 COMPOSITION CONTAINING LINEAR AMINOSILANE COMPOUND HAVING CARBOXYLIC ESTER GROUP AND CYCLIC SILAZANE COMPOUND HAVING CARBOXYLIC ESTER GROUP, AND METHOD FOR PRODUCING SAME 信越化学工業株式会社 2024-08-08 WO disclosed
US-8981080-B2 Silane-modified cationized polymeric compound and process for production thereof LION CORPORATION (JP) 2015-03-17 US disclosed
EP-2182009-B1 METHOD OF PRODUCING OF SILANE-MODIFIED CATIONIZED CELLULOSE LION CORP (JP) 2013-11-13 EP disclosed
US-8569263-B2 Method of producing silane-modified cationized cellulose LION CORPORATION (JP) 2013-10-29 US disclosed
US-20120065388-A1 SILANE-MODIFIED CATIONIZED POLYMERIC COMPOUND AND PROCESS FOR PRODUCTION THEREOF LION CORPORATION (JP) 2012-03-15 US disclosed
US-20110218336-A1 METHOD OF PRODUCING SILANE-MODIFIED CATIONIZED CELLULOSE LION CORPORATION (JP) 2011-09-08 US disclosed
US-20110212044-A1 CLEANSER COMPOSITION LION CORPORATION (JP) 2011-09-01 US disclosed
EP-2351553-A1 CLEANSER COMPOSITION Lion Corporation (JP) 2011-08-03 EP disclosed
EP-2182009-A1 PROCESS FOR PRODUCTION OF SILANE-MODIFIED CATIONIZED CELLULOSE Lion Corporation (JP) 2010-05-05 EP disclosed
US-4414272-A SILICA, EPOXIDE, SILANE COUPLER OR ORGANOTITANIUM COMPOUND TEIJIN LIMITED (JP) 1983-11-08 US disclosed
EP-0048481-A2 Shaped polyester composite material having an activated surface thereof and process for producing the same TEIJIN LIMITED (JP) 1982-03-31 EP disclosed