SCHEMBL4540177

SCHEMBL4540177

CCCC(OCC1CO1)[Si](OCC)(OCC)OCC.CCCC[Si](OC)(OC)OC

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TDP1 Q9NUW8 1/20 0.33
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2115593 0.88 ALDH1A1 (0.31) ALDH1A1
SCHEMBL188087 0.87 ALDH1A1 (0.37) ALDH1A1SMN1; SMN2TDP1
SCHEMBL12477662 0.84 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2TDP1
SCHEMBL16179849 0.83 ALDH1A1 (0.42) ALDH1A1SMN1; SMN2TDP1
SCHEMBL23501804 0.81 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2TDP1
SCHEMBL188243 0.80 SMN1; SMN2 (0.49) ALDH1A1SMN1; SMN2TDP1
SCHEMBL187672 0.79 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2TDP1
SCHEMBL5596957 0.78 SMN1; SMN2 (0.46) ALDH1A1SMN1; SMN2TDP1
SCHEMBL188498 0.77 SMN1; SMN2 (0.40) ALDH1A1SMN1; SMN2TDP1
SCHEMBL10948388 0.77 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2138501-B1 Functional silane compound, coating solution, and method for manufacturing plastic lens HOYA CORP (JP) 2014-08-13 EP disclosed
EP-2138501-A2 Functional silane compound, coating solution, and method for manufacturing plastic lens Hoya Corporation (JP) 2009-12-30 EP disclosed
US-20090317541-A1 FUNCTIONAL SILANE COMPOUND, COATING SOLUTION, AND METHOD FOR MANUFACTURING PLASTIC LENS HOYA CORPORATION (JP) 2009-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090317541-A1 FUNCTIONAL SILANE COMPOUND, COATING SOLUTION, AND METHOD FOR MANUFACTURING PLASTIC LENS SUMO1, CAD, UFM1 ALDH1A1 2829/4885SMN1; SMN2 3753/4885TDP1 4580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.