Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 6/20 | 0.42 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27489497 | 1.00 | NAAA (0.50) | NAAAEPHX1TSHRHCAR2RAD52 | |
| SCHEMBL19923362 | 0.87 | NAAA (0.48) | NAAAEPHX1TSHRHCAR2RAD52 | |
| SCHEMBL27815981 | 0.87 | NAAA (0.48) | NAAAEPHX1TSHRHCAR2RAD52 | |
| SCHEMBL15796608 | 0.84 | NAAA (0.46) | NAAAEPHX1TSHRHCAR2RAD52 | |
| Hydrochloric Acid SCHEMBL15569664 | 0.83 | NAAA (0.44) | NAAAEPHX1TSHRHCAR2RAD52 | |
| SCHEMBL3110769 | 0.82 | NAAA (0.47) | NAAAEPHX1TSHRHCAR2RAD52 | |
| SCHEMBL18510025 | 0.81 | ALDH1A1 (0.48) | NAAAEPHX1TSHRHCAR2DNM1 | |
| SCHEMBL15305326 | 0.79 | NAAA (0.52) | NAAAEPHX1TSHRHCAR2RAD52 | |
| SCHEMBL138880 | 0.79 | NAAA (0.52) | NAAAEPHX1TSHRHCAR2RAD52 | |
| SCHEMBL453610 | 0.79 | NAAA (0.52) | NAAAEPHX1TSHRHCAR2RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2613772-B1 | LOW-DOSE TRANSDERMAL PATCHES WITH HIGH DRUG RELEASE | BAYER IP GMBH (DE) | 2016-12-14 | — | — | EP | disclosed |
| US-9005653-B2 | Transdermal delivery of hormones with low concentration of penetration enhancers | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-04-14 | — | — | US | disclosed |
| US-20140109916-A1 | Transdermal Delivery of Hormones without the Need of Penetration Enhancers | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-04-24 | — | — | US | disclosed |
| US-8671945-B2 | Low-dose transdermal patches with high drug release | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-03-18 | — | — | US | disclosed |
| US-8668925-B2 | Transdermal delivery of hormones without the need of penetration enhancers | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-03-11 | — | — | US | disclosed |
| EP-2138169-B1 | Transdermal delivery system of hormones without penetration enhancers | BAYER IP GMBH (DE) | 2013-11-06 | — | — | EP | disclosed |
| EP-2613772-A2 | LOW-DOSE TRANSDERMAL PATCHES WITH HIGH DRUG RELEASE | Bayer Intellectual Property GmbH (DE) | 2013-07-17 | — | — | EP | disclosed |
| US-20120073578-A1 | LOW-DOSE TRANSDERMAL PATCHES WITH HIGH DRUG RELEASE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-29 | — | — | US | disclosed |
| WO-2012031999-A2 | LOW-DOSE TRANSDERMAL PATCHES WITH HIGH DRUG RELEASE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | WO | disclosed |
| EP-2138169-A2 | Transdermal delivery system of hormones without penetration enhancers | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-12-30 | — | — | EP | disclosed |
| US-20050142175-A1 | Transdermal delivery of hormones without the need of penetration enhancers | LUYE PHARMA SWITZERLAND AG (CH) | 2005-06-30 | — | — | US | disclosed |
| WO-2005058287-A2 | TRANSDERMAL DELIVERY SYSTEM OF HORMONES WITHOUT PENETRATION ENHANCERS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-06-30 | — | — | WO | disclosed |
| EP-1541137-A2 | Transdermal delivery system of hormones without penetration enhancers | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-06-15 | — | — | EP | disclosed |