Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.54 |
| ▸ | SLC28A1 | O00337 | 2/20 | 0.54 |
| ▸ | PI4KA | P42356 | 2/20 | 0.54 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.54 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.54 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.54 |
| ▸ | DPP4 | P27487 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.54 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.54 |
| ▸ | GAPDH | P04406 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.54 |
| ▸ | STAT6 | P42226 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.54 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27657118 | 1.00 | ADORA3 (0.54) | ADORA3ADORA2ASLC28A1PI4KAPI4K2B | |
| SCHEMBL23042807 | 1.00 | ADORA3 (0.54) | ADORA3ADORA2ASLC28A1PI4KAPI4K2B | |
| SCHEMBL27992710 | 1.00 | ADORA3 (0.54) | ADORA3ADORA2ASLC28A1PI4KAPI4K2B | |
| SCHEMBL5024893 | 1.00 | ADORA3 (0.54) | ADORA3ADORA2ASLC28A1PI4KAPI4K2B | |
| SCHEMBL1417403 | 1.00 | ADORA3 (0.54) | ADORA3ADORA2ASLC28A1PI4KAPI4K2B | |
| SCHEMBL27489485 | 0.99 | ADORA3 (0.53) | ADORA3ADORA2ASLC28A1PI4KAPI4K2B | |
| SCHEMBL31062627 | 0.86 | ADORA3 (0.55) | ADORA3ADORA2ASLC28A1PI4KAPI4K2B | |
| SCHEMBL481525 | 0.86 | ADORA3 (0.55) | ADORA3ADORA2ASLC28A1PI4KAPI4K2B | |
| SCHEMBL27541459 | 0.86 | PI4KA (0.39) | ADORA3ADORA2ASLC28A1PI4KAPI4K2B | |
| Homocysteine SCHEMBL28127837 | 0.86 | FASN (0.51) | KMT2ADOT1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945211-B1 | USE OF PYRROLOQUINOLINE COMPOUNDS TO KILL CLINICALLY LATENT MICROORGANISMS | HELPERBY THERAPEUTICS LTD (GB) | 2015-10-21 | — | — | EP | claimed |
| WO-2023057599-A1 | METHODS INVOLVING BACTEROIDES STRAIN REPLACEMENT | ELIGO BIOSCIENCE (FR) | 2023-04-13 | — | — | WO | disclosed |
| WO-2023057598-A1 | METHODS INVOLVING BACTERIAL STRAIN REPLACEMENT | ELIGO BIOSCIENCE (FR) | 2023-04-13 | — | — | WO | disclosed |
| WO-2021050564-A2 | THERAPEUTIC AGENTS AND METHODS FOR TREATMENT OF LYME DISEASE AND LYME DISEASE-RELATED DISORDERS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2021-03-18 | — | — | WO | disclosed |
| EP-3607084-A1 | A METHOD FOR TESTING ANTIMICROBIAL SUSCEPTIBILITY | The University Of Western Australia (AU) | 2020-02-12 | — | — | EP | disclosed |
| CN-110407892-A | A kind of preparation method of Vidarabine Monophosphate | GANSU TAISHENG CHEMICAL TECH CO LTD | 2019-11-05 | — | — | CN | disclosed |
| CN-106866763-B | A kind of synthesis technology of Vidarabine Monophosphate | 上海应用技术大学 | 2019-07-23 | — | — | CN | disclosed |
| WO-2018184073-A1 | A METHOD FOR TESTING ANTIMICROBIAL SUSCEPTIBILITY | THE UNIVERSITY OF WESTERN AUSTRALIA (AU) | 2018-10-11 | — | — | WO | disclosed |
| WO-2015155738-A2 | USE OF GSK-3 INHIBITORS OR ACTIVATORS WHICH MODULATE PD-1 OR T-BET EXPRESSION TO MODULATE T CELL IMMUNITY | RUDD CHRISTOPHER (US) | 2015-10-15 | — | — | WO | disclosed |
| CN-101128738-B | Analytical method | AXIS-SHIELD ASA (NO) | 2014-10-01 | — | — | CN | disclosed |
| EP-2624817-A1 | NOVEL COMPOSITION | Helperby Therapeutics Limited (GB) | 2013-08-14 | — | — | EP | disclosed |
| EP-2613774-A2 | NOVEL USE | Helperby Therapeutics Limited (GB) | 2013-07-17 | — | — | EP | disclosed |
| EP-2600869-A1 | COMBINATION OF A PYRROLOQUINOLINE COMPOUND AND A BETA-LACTAM ANTIMICROBIAL AGENT, MUPIROCIN OR CHLORHEXIDINE | Helperby Therapeutics Limited (GB) | 2013-06-12 | — | — | EP | disclosed |
| EP-2552440-A1 | NOVEL COMBINATION AND USE | Helperby Therapeutics Limited (GB) | 2013-02-06 | — | — | EP | disclosed |
| WO-2012153130-A1 | SALTS OF 4 -ETHYL-1-(2 - PHENYLETHYL) - 8 -PHENOXY - 2, 3 - DIHYDRO - 1H - PYRROLO [3, 2 -C] QUINOLINE AND THEIR USE FOR TREATING INFECTIONS | HELPERBY THERAPEUTICS LIMITED (GB) | 2012-11-15 | — | — | WO | disclosed |
| WO-2012046078-A1 | NOVEL COMPOSITION | HELPERBY THERAPEUTICS LIMITED (GB) | 2012-04-12 | — | — | WO | disclosed |
| WO-2012032360-A2 | NOVEL USE | HELPERBY THERAPEUTICS LIMITED (GB) | 2012-03-15 | — | — | WO | disclosed |
| WO-2012017215-A1 | COMBINATION OF A PYRROLOQUINOLINE COMPOUND AND A BETA-LACTAM ANTIMICROBIAL AGENT, MUPIROCIN OR CHLORHEXIDINE | HELPERBY THERAPEUTICS LIMITED (GB) | 2012-02-09 | — | — | WO | disclosed |
| WO-2011121345-A1 | NOVEL COMBINATION AND USE | HELPERBY THERAPEUTICS LIMITED (GB) | 2011-10-06 | — | — | WO | disclosed |
| CN-101128738-A | Analytical method | AXIS SHIELD ASA (NO) | 2008-02-20 | — | — | CN | disclosed |