SCHEMBL5024893

SCHEMBL5024893

Nc1ncnc2c1ncn2[C@]1(O)O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 5/20 0.54
ADORA2A P29274 3/20 0.54
SLC28A1 O00337 2/20 0.54
PI4KA P42356 2/20 0.54
PI4K2B Q8TCG2 2/20 0.54
PI4K2A Q9BTU6 2/20 0.54
PI4KB Q9UBF8 2/20 0.54
DPP4 P27487 1/20 0.54
MEN1 O00255 1/20 0.54
MAP3K7 O43318 1/20 0.54
SLC28A2 O43868 1/20 0.54
GAPDH P04406 1/20 0.54
MAPK1 P28482 1/20 0.54
ADORA2B P29275 1/20 0.54
ADORA1 P30542 1/20 0.54
STAT6 P42226 1/20 0.54
KMT2A Q03164 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
DOT1L Q8TEK3 1/20 0.54
SLC29A1 Q99808 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27657118 1.00 ADORA3 (0.54) ADORA3ADORA2ASLC28A1PI4KAPI4K2B
SCHEMBL23042807 1.00 ADORA3 (0.54) ADORA3ADORA2ASLC28A1PI4KAPI4K2B
SCHEMBL27992710 1.00 ADORA3 (0.54) ADORA3ADORA2ASLC28A1PI4KAPI4K2B
SCHEMBL454216 1.00 ADORA3 (0.54) ADORA3ADORA2ASLC28A1PI4KAPI4K2B
SCHEMBL1417403 1.00 ADORA3 (0.54) ADORA3ADORA2ASLC28A1PI4KAPI4K2B
SCHEMBL27489485 0.99 ADORA3 (0.53) ADORA3ADORA2ASLC28A1PI4KAPI4K2B
SCHEMBL31062627 0.86 ADORA3 (0.55) ADORA3ADORA2ASLC28A1PI4KAPI4K2B
SCHEMBL481525 0.86 ADORA3 (0.55) ADORA3ADORA2ASLC28A1PI4KAPI4K2B
SCHEMBL27541459 0.86 PI4KA (0.39) ADORA3ADORA2ASLC28A1PI4KAPI4K2B
Homocysteine SCHEMBL28127837 0.86 FASN (0.51) KMT2ADOT1L

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104686208-A Usage and method for detection, processing and artificial cultivation of tussah cordyceps militaris taken as traditional Chinese medicinal materials BEIJING MAILLARD TRADITIONAL CHINESE MEDICINE DECOCTION PIECES TECHNOLOGY CO LTD 2015-06-10 CN claimed
US-20250223620-A1 NOVEL PROCESSES FOR THE PRODUCTION OF POLYNUCLEOTIDES INCLUDING OLIGONUCLEOTIDES GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2025-07-10 US disclosed
EP-4504932-A1 NOVEL PROCESSES FOR THE PRODUCTION OF POLYNUCLEOTIDES INCLUDING OLIGONUCLEOTIDES GlaxoSmithKline Intellectual Property Development Ltd (GB) 2025-02-12 EP disclosed
CN-119013398-A Novel method for producing polynucleotides comprising oligonucleotides 葛兰素史密斯克莱知识产权发展有限公司 2024-11-22 CN disclosed
US-11976296-B2 Means and methods for generating midbrain organoids UNIVERSITÉ DU LUXEMBOURG (LU) 2024-05-07 US disclosed
WO-2023194537-A1 NOVEL PROCESSES FOR THE PRODUCTION OF POLYNUCLEOTIDES INCLUDING OLIGONUCLEOTIDES GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2023-10-12 WO disclosed
CN-104686208-B A kind of artificial culturing method of toothed oak Cordyceps militaris Chinese medicine, processing, detection and application thereof 北京美拉德中药饮片科技有限公司 2019-08-23 CN disclosed
CN-106478754-A The preparation method of 2 ' O only son's acyl adenosine cyclophosphate 上海上药第生化药业有限公司 2017-03-08 CN disclosed
CN-104686208-A Usage and method for detection, processing and artificial cultivation of tussah cordyceps militaris taken as traditional Chinese medicinal materials BEIJING MAILLARD TRADITIONAL CHINESE MEDICINE DECOCTION PIECES TECHNOLOGY CO LTD 2015-06-10 CN disclosed
CN-104686208-A Usage and method for detection, processing and artificial cultivation of tussah cordyceps militaris taken as traditional Chinese medicinal materials BEIJING MAILLARD TRADITIONAL CHINESE MEDICINE DECOCTION PIECES TECHNOLOGY CO LTD 2015-06-10 CN disclosed
EP-1903873-A2 HERPES VIRUS-BASED COMPOSITIONS AND METHODS OF USE IN THE PRENATAL AND PERINATAL PERIODS THE UNIVERSITY OF ROCHESTER (US) 2008-04-02 EP disclosed
WO-2006135602-A2 HERPES VIRUS-BASED COMPOSITIONS AND METHODS OF USE IN THE PRENATAL AND PERINATAL PERIODS UNIVERSITY OF ROCHESTER (US) 2006-12-21 WO disclosed
US-7049303-B2 Inhibition of viruses MEDICAL RESEARCH COUNCIL (GB) 2006-05-23 US disclosed
US-20050043268-A1 Inhibition of viruses MEDICAL RESEARCH COUNCIL (GB) 2005-02-24 US disclosed
WO-1998001459-A1 NOVEL N-ALKOXYADENINE DERIVATIVES ACTING AS CYTOKINE INHIBITORS NOVO NORDISK A/S (DK) 1998-01-15 WO disclosed
WO-1997033590-A1 A METHOD OF TREATING DISORDERS RELATED TO CYTOKINES IN MAMMALS NOVO NORDISK A/S (DK) 1997-09-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050043268-A1 Inhibition of viruses RNASE1, HNRNPA1, RNASEH1 ADORA3 399/4885ADORA2A 282/4885SLC28A1 102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.