Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NCF1 | P14598 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4537249 | 0.88 | ALDH1A1 (0.37) | ALDH1A1NCF1KDM1AALOX15L3MBTL1 | |
| SCHEMBL4537842 | 0.88 | ALDH1A1 (0.33) | ALDH1A1NCF1KDM1AALOX15L3MBTL1 | |
| SCHEMBL4542445 | 0.85 | ALDH1A1 (0.34) | ALDH1A1NCF1KDM1AALOX15L3MBTL1 | |
| SCHEMBL4535601 | 0.85 | — | — | |
| SCHEMBL16538765 | 0.76 | ALDH1A1 (0.42) | ALDH1A1NCF1KDM1AALOX15L3MBTL1 | |
| SCHEMBL737934 | 0.75 | — | — | |
| SCHEMBL1394992 | 0.74 | L3MBTL1 (0.41) | ALDH1A1NCF1KDM1AALOX15L3MBTL1 | |
| SCHEMBL23588994 | 0.72 | ALDH1A1 (0.34) | ALDH1A1NCF1L3MBTL1 | |
| SCHEMBL735446 | 0.72 | SLC18A3 (0.35) | ALDH1A1L3MBTL1 | |
| SCHEMBL4534766 | 0.72 | ALDH1A1 (0.40) | ALDH1A1NCF1KDM1AALOX15L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009071691-A2 | OXINDOLE DERIVATIVES AND THE USE THEREOF AS A MEDICATION | ABBOTT GMBH & CO. KG (DE) | 2009-06-11 | — | — | WO | disclosed |