⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5314785 | 0.94 | LMNA (0.36) | — | |
| SCHEMBL196492 | 0.91 | HRH3 (0.39) | — | |
| SCHEMBL3316329 | 0.91 | HRH3 (0.39) | — | |
| Hydrochloric Acid SCHEMBL25233214 | 0.88 | ALDH1A1 (0.38) | — | |
| SCHEMBL25235628 | 0.87 | KDM1A (0.34) | — | |
| SCHEMBL12617201 | 0.85 | TSHR (0.36) | — | |
| Hydrochloric Acid SCHEMBL25234812 | 0.84 | KDM1A (0.33) | — | |
| SCHEMBL30341319 | 0.84 | KDM4E (0.31) | — | |
| SCHEMBL2606082 | 0.83 | KDM4E (0.46) | — | |
| SCHEMBL12337635 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260070879-A1 | ISOXAZOLINE DERIVATIVES | ELANCO TIERGESUNDHEIT AG (CH) | 2026-03-12 | — | — | US | claimed |
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | HK INNO.N CORPORATION (KR) | 2022-12-13 | — | — | US | claimed |
| CN-114656485-A | Preparation method of trifluoroethyl-containing azetidine derivative | 浙江师范大学 | 2022-06-24 | — | — | CN | claimed |
| CN-113200999-A | Derivative containing trifluoroethyl azetidine and preparation method thereof | 浙江师范大学 | 2021-08-03 | — | — | CN | claimed |
| US-20260132109-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | NOVARTIS PHARMA AG (CH) | 2026-05-14 | — | — | US | disclosed |
| US-12503436-B2 | Compounds and compositions for treating conditions associated with STING activity | NOVARTIS PHARMA AG (CH) | 2025-12-23 | — | — | US | disclosed |
| US-12221436-B2 | Anthranilamides, their use as insecticide and processes for preparing the same | PI INDUSTRIES LTD. (IN) | 2025-02-11 | — | — | US | disclosed |
| US-20240109903-A1 | SUBSTITUTED HETEROCYCLES FOR TREATING CANCER | NORTHWESTERN UNIVERSITY | 2024-04-04 | — | — | US | disclosed |
| US-11919915-B2 | Compounds and methods useful for stabilizing phenylalanine hydroxylase mutations | AGIOS PHARMACEUTICALS, INC. (US) | 2024-03-05 | — | — | US | disclosed |
| US-20230339980-A1 | COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS | AGIOS PHARMACEUTICALS, INC. (US) | 2023-10-26 | — | — | US | disclosed |
| US-20230250106-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | NOVARTIS PHARMA AG (CH) | 2023-08-10 | — | — | US | disclosed |
| US-20230167057-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | NOVARTIS PHARMA AG (CH) | 2023-06-01 | — | — | US | disclosed |
| CN-113200999-A | Derivative containing trifluoroethyl azetidine and preparation method thereof | 浙江师范大学 | 2021-08-03 | — | — | CN | disclosed |
| CN-113200999-A | Derivative containing trifluoroethyl azetidine and preparation method thereof | 浙江师范大学 | 2021-08-03 | — | — | CN | disclosed |
| CN-113200999-A | Derivative containing trifluoroethyl azetidine and preparation method thereof | 浙江师范大学 | 2021-08-03 | — | — | CN | disclosed |
| CN-108349946-B | Quinoxaline and pyridopyrazine derivatives as PI3K beta inhibitors | 詹森药业有限公司 | 2021-05-18 | — | — | CN | disclosed |
| CN-107922379-A | Substituted guanidine derivatives | 宇部兴产株式会社 | 2018-04-17 | — | — | CN | disclosed |
| CN-107438603-A | Pyrazole compounds and methods of making and using the same | 里格尔药品股份有限公司 | 2017-12-05 | — | — | CN | disclosed |
| EP-2638031-A1 | PYRAZOLE AMINOPYRIMIDINE DERIVATIVES AS LRRK2 MODULATORS | F.HOFFMANN-LA ROCHE AG (CH) | 2013-09-18 | — | — | EP | disclosed |
| WO-2012062783-A1 | PYRAZOLE AMINOPYRIMIDINE DERIVATIVES AS LRRK2 MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-05-18 | — | — | WO | disclosed |