Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4542552 | 0.92 | PTGER4 (0.49) | MAPK14CYP3A4CNR2PTGER4LIPG | |
| SCHEMBL4540508 | 0.89 | CNR2 (0.44) | MAPK14CYP3A4CNR2PTGER4LIPG | |
| SCHEMBL4542152 | 0.89 | CNR2 (0.44) | MAPK14CYP3A4CNR2PTGER4LIPG | |
| SCHEMBL4543780 | 0.87 | CNR2 (0.47) | MAPK14CYP3A4CNR2PTGER4LIPG | |
| SCHEMBL4540261 | 0.86 | LIPG (0.45) | MAPK14CYP3A4CNR2PTGER4LIPG | |
| SCHEMBL4543796 | 0.85 | LIPG (0.43) | MAPK14CYP3A4CNR2PTGER4LIPG | |
| SCHEMBL4543848 | 0.85 | CNR2 (0.42) | MAPK14CYP3A4CNR2PTGER4LIPG | |
| SCHEMBL4544135 | 0.85 | LIPG (0.43) | MAPK14CYP3A4CNR2PTGER4LIPG | |
| SCHEMBL4539900 | 0.84 | ALDH1A1 (0.43) | MAPK14CYP3A4CNR2LIPG | |
| SCHEMBL4542684 | 0.84 | LIPG (0.43) | MAPK14CYP3A4CNR2PTGER4LIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |