Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.39 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.39 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.39 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 11/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17018453 | 0.74 | NOS1 (0.42) | FDPSNOS1CTSASLC6A3 | |
| SCHEMBL4540382 | 0.74 | CTSA (0.39) | NOS1CTSA | |
| SCHEMBL17018479 | 0.74 | NOS1 (0.42) | FDPSNOS1CTSASLC6A3 | |
| Hydrochloric Acid SCHEMBL17007845 | 0.73 | NOS1 (0.41) | FDPSNOS1CTSASLC6A3 | |
| SCHEMBL8945917 | 0.71 | NOS1 (0.34) | CACNA2D1NOS1CTSASLC6A3 | |
| SCHEMBL3696916 | 0.71 | KDM4E (0.38) | CACNA2D1FDPSNOS1CTSASLC6A3 | |
| SCHEMBL20292577 | 0.69 | CACNA2D1 (0.45) | CACNA2D1FDPSNOS1CTSASLC6A3 | |
| SCHEMBL12179253 | 0.69 | — | — | |
| SCHEMBL765512 | 0.68 | — | — | |
| SCHEMBL19504364 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064269-A1 | COMPOUNDS AND THEIR USE FOR TREATMENT OF Αβ-RELATED DISEASES | ASTRAZENECA AB (SE) | 2012-05-18 | — | — | WO | disclosed |