Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15821855 | 0.77 | P2RX7 (0.31) | APLNR | |
| SCHEMBL26741297 | 0.76 | APLNR (0.32) | APLNR | |
| SCHEMBL24323983 | 0.76 | APLNR (0.32) | APLNR | |
| Hydrochloric Acid SCHEMBL17288074 | 0.76 | P2RX7 (0.30) | — | |
| Hydrochloric Acid SCHEMBL17288072 | 0.76 | P2RX7 (0.30) | — | |
| SCHEMBL31564833 | 0.73 | — | — | |
| SCHEMBL26829544 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL31564573 | 0.71 | APLNR (0.32) | APLNR | |
| SCHEMBL11464254 | 0.71 | RECQL (0.32) | — | |
| SCHEMBL24386937 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064269-A1 | COMPOUNDS AND THEIR USE FOR TREATMENT OF Αβ-RELATED DISEASES | ASTRAZENECA AB (SE) | 2012-05-18 | — | — | WO | disclosed |