Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 7/20 | 0.75 |
| ▸ | PSMB5 | P28074 | 7/20 | 0.75 |
| ▸ | PSMB2 | P49721 | 5/20 | 0.75 |
| ▸ | LTA4H | P09960 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | ESR1 | P03372 | 2/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.58 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | GCGR | P47871 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8475814 | 0.99 | PSMB1 (0.73) | PSMB1PSMB5PSMB2LTA4HKDM4E | |
| Water SCHEMBL8476776 | 0.99 | PSMB1 (0.73) | PSMB1PSMB5PSMB2LTA4HKDM4E | |
| SCHEMBL7443953 | 0.99 | PSMB1 (0.78) | PSMB1PSMB5PSMB2LTA4HKDM4E | |
| Water SCHEMBL8476448 | 0.97 | PSMB1 (0.76) | PSMB1PSMB5PSMB2LTA4HKDM4E | |
| Hydrochloric Acid SCHEMBL7451065 | 0.97 | PSMB1 (0.76) | PSMB1PSMB5PSMB2LTA4HKDM4E | |
| SCHEMBL7450424 | 0.94 | KDM4E (0.67) | PSMB1PSMB5PSMB2LTA4HKDM4E | |
| SCHEMBL8337044 | 0.93 | KDM4E (0.68) | PSMB1PSMB5PSMB2LTA4HKDM4E | |
| SCHEMBL7447270 | 0.89 | SMN1; SMN2 (0.61) | PSMB1PSMB5PSMB2LTA4HKDM4E | |
| SCHEMBL8641421 | 0.88 | PSMB1 (0.62) | PSMB1PSMB5PSMB2LTA4HKDM4E | |
| SCHEMBL6597214 | 0.88 | PSMB1 (0.97) | PSMB1PSMB5PSMB2LTA4HKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104994877-A | Trans-clomiphene for cancer treatment | REPROS THERAPEUTICS INC | 2015-10-21 | — | — | CN | disclosed |
| CN-104244953-A | Combination therapy for treating androgen deficiency | REPROS THERAPEUTICS INC | 2014-12-24 | — | — | CN | disclosed |
| EP-2637649-A2 | COMPOUNDS AND METHODS FOR TREATING PAIN | Akron Molecules GmbH (AT) | 2013-09-18 | — | — | EP | disclosed |
| CN-102940619-A | Trans-clomiphene for metabolic syndrome | REPROS THERAPEUTICS INC | 2013-02-27 | — | — | CN | disclosed |
| CN-101896174-B | Pearl clomiphene for treating metabolic syndrome | REPROS THERAPEUTICS INC | 2012-10-31 | — | — | CN | disclosed |
| WO-2012062925-A2 | COMPOUNDS AND METHODS FOR TREATING PAIN | AKRON MOLECULES GMBH (AT) | 2012-05-18 | — | — | WO | disclosed |
| CN-101896174-A | Pearl clomiphene for treating metabolic syndrome | REPROS THERAPEUTICS INC | 2010-11-24 | — | — | CN | disclosed |
| EP-0993300-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2002-07-31 | — | — | EP | disclosed |
| EP-0973517-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2002-07-24 | — | — | EP | disclosed |
| EP-1027051-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2001-03-07 | — | — | EP | disclosed |
| EP-0973517-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-01-26 | — | — | EP | disclosed |
| US-5958969-A | OSTEOPOROSIS | ELI LILLY AND COMPANY (US) | 1999-09-28 | — | — | US | disclosed |
| US-5948796-A | OSTEOPOROSIS, CANCER, CARDIOVASCULAR DISORDERS | ELI LILLY AND COMPANY (US) | 1999-09-07 | — | — | US | disclosed |
| EP-0863755-A4 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 1999-01-20 | — | — | EP | disclosed |
| WO-1998048798-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |
| WO-1998048794-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |
| WO-1998048804-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |
| WO-1998049160-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |
| EP-0863755-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997025033-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |