SCHEMBL4543189

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4791340	0.88	BRD4 (0.47)	BRD4MTORPIK3CDPIK3CATLR7
	SCHEMBL4790722	0.87	BRD4 (0.52)	BRD4MTORPIK3CDPIK3CATLR7
	SCHEMBL14466847	0.85	TLR7 (0.54)	BRD4MTORPIK3CDPIK3CATLR7
	SCHEMBL1486838	0.83	BRD4 (0.46)	BRD4MTORPIK3CDPIK3CATLR7
	SCHEMBL14466855	0.83	BRD4 (0.43)	BRD4MTORPIK3CDPIK3CATLR7
	SCHEMBL4763017	0.82	BRD4 (0.44)	BRD4MTORPIK3CDPIK3CATLR7
	SCHEMBL4763020	0.82	BRD4 (0.44)	BRD4MTORPIK3CDPIK3CATLR7
	SCHEMBL4242646	0.82	TLR7 (0.61)	TLR7TLR8
	SCHEMBL14465892	0.81	CNR2 (0.42)	BRD4MTORPIK3CDPIK3CATLR7
	SCHEMBL14466064	0.80	BRD4 (0.46)	BRD4MTORPIK3CDPIK3CATLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.