SCHEMBL45432

SCHEMBL45432

C=CCc1ccc(O)c(CC=C)c1CC=C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 5/20 0.53
GABRB2 P47870 5/20 0.53
SRD5A1 P18405 2/20 0.46
POLB P06746 2/20 0.46
XDH P47989 2/20 0.45
CNR2 P34972 3/20 0.44
ALDH1A1 P00352 3/20 0.44
MEN1 O00255 2/20 0.44
GAA P10253 2/20 0.44
MAPT P10636 2/20 0.44
CNR1 P21554 2/20 0.44
KMT2A Q03164 2/20 0.44
AKR1B1 P15121 2/20 0.44
HPGD P15428 2/20 0.44
KDM4E B2RXH2 1/20 0.44
ALDH2 P05091 1/20 0.44
PPARG P37231 1/20 0.44
PPARD Q03181 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
ALOX5 P09917 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9297409 0.98 GABRA1 (0.52) GABRA1GABRB2SRD5A1POLBXDH
SCHEMBL11820117 0.94 GABRA1 (0.48) GABRA1GABRB2SRD5A1POLBXDH
SCHEMBL1194767 0.89 GABRA1 (0.47) GABRA1GABRB2SRD5A1POLBXDH
SCHEMBL323547 0.89 XDH (0.54) GABRA1GABRB2SRD5A1POLBXDH
SCHEMBL10907261 0.88 GABRA1 (0.47) GABRA1GABRB2SRD5A1POLBXDH
SCHEMBL11883899 0.88 GABRA1 (0.43) GABRA1GABRB2SRD5A1POLBXDH
Hydrogen Sulfide SCHEMBL6721312 0.86 XDH (0.52) GABRA1GABRB2SRD5A1POLBXDH
SCHEMBL1918099 0.86 GABRA1 (0.43) GABRA1GABRB2SRD5A1POLBXDH
SCHEMBL4012043 0.85 GABRA1 (0.52) GABRA1GABRB2SRD5A1POLBXDH
SCHEMBL7943871 0.85 GABRA1 (0.52) GABRA1GABRB2SRD5A1POLBXDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2304 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117165210-A EVA adhesive film and preparation method thereof 福建惠亿美环保材料科技有限公司 2023-12-05 CN claimed
EP-3581598-B1 BIOPOLYMERS AND PREPARATION METHOD INGELIA S L (ES) 2023-09-13 EP claimed
CN-111479831-B Hydrogenation of nitrile rubber latex 阿朗新科德国有限责任公司 2023-02-03 CN claimed
EP-3728337-B1 HYDROGENATION OF NITRILE BUTADIENE RUBBER LATEX ARLANXEO DEUTSCHLAND GMBH (DE) 2022-02-09 EP claimed
US-11225533-B2 Hydrogenation of nitrile butadiene rubber latex ARLANXEO DEUTSCHLAND GMBH (DE) 2022-01-18 US claimed
EP-3728337-A1 HYDROGENATION OF NITRILE BUTADIENE RUBBER LATEX ARLANXEO Deutschland GmbH (DE) 2020-10-28 EP claimed
US-20200308312-A1 HYDROGENATION OF NITRILE BUTADIENE RUBBER LATEX ARLANXEO DEUTSCHLAND GMBH (DE) 2020-10-01 US claimed
CN-111479831-A Hydrogenation of nitrile rubber latex 阿朗新科德国有限责任公司 2020-07-31 CN claimed
EP-3394027-B1 METHOD FOR PREPARING PHENOLICS USING A CATALYST TNO (NL) 2020-02-19 EP claimed
CN-107207999-B Lightening compositions 荷兰联合利华有限公司 2019-09-27 CN claimed
US-5224988-A Precipitation in coagulum with a surfactant for improving dispersibility and filterability SOCIETE NATIONALE ELF AQUITAINE (FR) 1993-07-06 US claimed
US-5116715-A Contrast, resolution, photoresists U C B S.A. (BE) 1992-05-26 US claimed
EP-0204659-B1 POLYEPOXYDES AND THEIR USE CIBA-GEIGY AG (CH) 1991-11-21 EP claimed
EP-0372321-A1 Polyphenylene ether-high impact polystyrene blends GENERAL ELECTRIC COMPANY (US) 1990-06-13 EP claimed
EP-0335220-A2 Positive-working light-sensitive mixture and recording material of high thermal stability prepared therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1989-10-04 EP claimed
EP-0323427-A2 Light-sensitive compositions with phenol resins and quinone diarides U C B, S.A. (BE) 1989-07-05 EP claimed
US-4677170-A Polyepoxides and the use thereof CIBA-GEIGY CORPORATON (US) 1987-06-30 US claimed
EP-0216213-A2 Discoloration inhibitor for aromatic amines ETHYL CORPORATION (US) 1987-04-01 EP claimed
EP-0204659-A2 Polyepoxydes and their use CIBA-GEIGY AG (CH) 1986-12-10 EP claimed
US-4572721-A AMINES WITH ETHYLENE OXIDE UNITS AND NON-IONIC EMULSIFIERS SANDOZ LTD. (CH) 1986-02-25 US claimed