SCHEMBL454324

SCHEMBL454324

CCOP(=O)(Cc1ccc(C(=O)O)cc1)OCC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.53
RXRA P19793 2/20 0.45
RXRB P28702 2/20 0.45
HDAC1 Q13547 1/20 0.45
RARB P10826 6/20 0.44
SMN1; SMN2 Q16637 3/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
PLA2G4B P0C869 1/20 0.42
NPY5R Q15761 1/20 0.42
KMT2A Q03164 3/20 0.42
POLB P06746 2/20 0.41
MEN1 O00255 2/20 0.41
MAPT P10636 2/20 0.41
RARA P10276 1/20 0.41
MTOR P42345 1/20 0.41
TP53 P04637 1/20 0.41
TSHR P16473 1/20 0.41
KDM4E B2RXH2 1/20 0.41
USP2 O75604 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL917302 0.95 RARB (0.51) ALDH1A1RXRARXRBHDAC1RARB
SCHEMBL8671829 0.87 ALDH1A1 (0.50) ALDH1A1RXRARXRBRARBSMN1; SMN2
SCHEMBL8671670 0.86 HDAC1 (0.45) ALDH1A1HDAC1NPY5RKMT2APOLB
SCHEMBL1987238 0.86 KMT2A (0.50) ALDH1A1HDAC1SMN1; SMN2RAB9ANPY5R
SCHEMBL915443 0.86 ALDH1A1 (0.53) ALDH1A1RXRARXRBHDAC1RARB
SCHEMBL9440266 0.85 ALDH1A1 (0.49) ALDH1A1HDAC1SMN1; SMN2RAB9ANPY5R
SCHEMBL3375825 0.85 TSHR (0.50) HDAC1NPY5RPOLBMAPTTP53
SCHEMBL6421415 0.85 HDAC1 (0.44) ALDH1A1HDAC1NPY5RKMT2APOLB
SCHEMBL5276387 0.85 PARP10 (0.50) ALDH1A1HDAC1SMN1; SMN2NPC1RAB9A
SCHEMBL6029830 0.85 HDAC1 (0.44) ALDH1A1HDAC1NPY5RKMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109265700-B Chiral supermolecule metal phosphonate crystal material, preparation method and application 辽宁师范大学 2021-06-11 CN claimed
US-20250298333-A1 POLYESTER RESIN COMPOSITION, ELECTROSTATIC CHARGE IMAGE DEVELOPING TONER, DEVELOPER, AND IMAGE FORMING METHOD Konica Minolta, Inc. (JP) 2025-09-25 US disclosed
CN-109265700-B Chiral supermolecule metal phosphonate crystal material, preparation method and application 辽宁师范大学 2021-06-11 CN disclosed
US-10036744-B2 Bifunctional acid monolayers for the selective placement of carbon nanotubes INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-07-31 US disclosed
US-20170176427-A1 Bifunctional Acid Monolayers for the Selective Placement of Carbon Nanotubes INTERNATIONAL BUSINESS MACHINES CORPORATION 2017-06-22 US disclosed
US-20170176427-A1 Bifunctional Acid Monolayers for the Selective Placement of Carbon Nanotubes INTERNATIONAL BUSINESS MACHINES CORPORATION 2017-06-22 US disclosed
CN-102471366-B 17-hydroxy-17-pentafluoroethylestra-4, 9(10) -diene 11-benzylidene derivatives, process for preparing them and their use for treating diseases BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-12-16 CN disclosed
US-9156877-B2 17-hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-benzylidene derivatives, methods for the production thereof and use thereof for treating diseases BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-10-13 US disclosed
EP-2456782-B1 17-HYDROXY-17-PENTAFLUORETHYL-ESTRA-4,9(10)-DIEN-11-BENZYLIDENE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF AND USE THEREOF FOR TREATING DISEASES BAYER IP GMBH (DE) 2015-08-19 EP disclosed
US-8445695-B2 Synthesis of phosphono-substituted porphyrin compounds for attachment to metal oxide surfaces NORTH CAROLINA STATE UNIVERSITY (US) 2013-05-21 US disclosed
WO-1994017796-A1 THERAPEUTIC USE OF COMPOUNDS HAVING SELECTIVE AGONIST-LIKE ACTIVITY ON RXR RETINOID RECEPTORS ALLERGAN, INC. (US) 1994-08-18 WO disclosed
EP-0315071-B1 Benzocyclohepten derivatives, their preparation and utilisation for pharmaceutics HOFFMANN LA ROCHE (CH) 1994-07-20 EP disclosed
US-5324840-A Skin disorders ALLERGAN, INC. (US) 1994-06-28 US disclosed
EP-0313002-B1 Phenyl glycines for use in reducing neurotoxic injury SEARLE & CO (US) 1993-12-01 EP disclosed
US-5235076-A Anticarcinogenic agents UNIVERSITY OF HAWAII (US) 1993-08-10 US disclosed
US-4971957-A ANTILIPEMIC AGENTS, ANTICHOLESTEROL AGENTS, BENZENECARBOXAMIDOPHOSPHONATES OR BENZENETHIOCARBOXAMIDOPHOSPHONATES OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 1990-11-20 US disclosed
US-4918064-A TREATMENT OF ANOXIA OR ISCHEMIA G. D. SEARLE & CO. (US) 1990-04-17 US disclosed
EP-0315071-A2 Benzocyclohepten derivatives, their preparation and utilisation for pharmaceutics F. HOFFMANN-LA ROCHE AG (CH) 1989-05-10 EP disclosed
EP-0313002-A2 Phenyl glycines for use in reducing neurotoxic injury G.D. Searle & Co. (US) 1989-04-26 EP disclosed
US-4822780-A CALCIUM ANTAGONIST, ANTIINFLAMMATORY AGENT OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 1989-04-18 US disclosed