Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 7/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7885338 | 0.84 | KEAP1 (0.33) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL9620593 | 0.84 | KEAP1 (0.33) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL7784207 | 0.78 | — | — | |
| SCHEMBL17961079 | 0.78 | — | — | |
| SCHEMBL7784206 | 0.78 | ALDH1A1 (0.30) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL7885340 | 0.77 | HCAR2 (0.43) | ALDH1A1TP53TSHRLMNA | |
| SCHEMBL9620594 | 0.77 | HCAR2 (0.43) | ALDH1A1TP53TSHRLMNA | |
| SCHEMBL221767 | 0.76 | — | — | |
| SCHEMBL14983013 | 0.76 | ALDH1A1 (0.43) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL27713669 | 0.76 | ALDH1A1 (0.38) | ALDH1A1TP53HIF1ACYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4214253-A1 | ULTRAVIOLET-ABSORBING ACRYLIC COPOLYMER FOR THE PRODUCTION OF FLEXIBLE INTRAOCULAR LENS | Acrylian (FR) | 2023-07-26 | — | — | EP | claimed |
| CN-108348642-B | Hydrophobic, crosslinked and cinnamyl alcohol-based acrylic copolymers for intraocular lenses | 阿库里恩公司 | 2022-01-28 | — | — | CN | claimed |
| US-10626206-B2 | Acrylic copolymer, which is hydrophobic, cross-linked and based on cinnamic alcohol, for intraocular lenses | ACRYLIAN (FR) | 2020-04-21 | — | — | US | claimed |
| EP-3373992-B1 | ACRYLIC COPOLYMER, WHICH IS HYDROPHOBIC, CROSS-LINKED AND BASED ON CINNAMIC ALCOHOL, FOR INTRAOCULAR LENSES | ACRYLIAN (FR) | 2020-04-08 | — | — | EP | claimed |
| US-20180312619-A1 | ACRYLIC COPOLYMER, WHICH IS HYDROPHOBIC, CROSS-LINKED AND BASED ON CINNAMIC ALCOHOL, FOR INTRAOCULAR LENSES | ACRYLIAN (FR) | 2018-11-01 | — | — | US | claimed |
| US-9907881-B2 | Crosslinked, hydrophobic acrylic copolymer made of 2-phenoxytetraethylene-glycol acrylate and intended for intraocular lenses | ACRYLIAN (FR) | 2018-03-06 | — | — | US | claimed |
| EP-3110464-B1 | CROSSLINKED, HYDROPHOBIC ACRYLIC COPOLYMER MADE OF 2-PHENOXY-TETRAETHYLENE-GLYCOL ACRYLATE AND INTENDED FOR INTRAOCULAR LENSES | ACRYLIAN (FR) | 2017-11-01 | — | — | EP | claimed |
| US-20160331864-A1 | CROSSLINKED, HYDROPHOBIC ACRYLIC COPOLYMER MADE OF 2- PHENOXYTETRAETHYLENE-GLYCOL ACRYLATE AND INTENDED FOR INTRAOCULAR LENSES | ACRYLIAN (FR) | 2016-11-17 | — | — | US | claimed |
| US-4379864-A | Polymeric compositions and hydrogels formed therefrom | SYNTEX (U.S.A.) INC. (US) | 1983-04-12 | — | — | US | claimed |
| US-4267295-A | Polymeric compositions and hydrogels formed therefrom | SYNTEX (U.S.A.) INC. (US) | 1981-05-12 | — | — | US | claimed |
| US-4180308-A | Contact lens | SYNTEX (USA) INC. (US) | 1979-12-25 | — | — | US | claimed |
| US-4105448-A | BINDER OF EPOXY ESTER RESIN WITH AN ACRYLIC ESTER COPOLYMER | FUJI PHOTO FILM CO., LTD. (JP) | 1978-08-08 | — | — | US | claimed |
| US-11998481-B2 | Methods and compositions for iontophoretic drug delivery to the eye | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION INC. (US) | 2024-06-04 | — | — | US | disclosed |
| EP-4214253-A1 | ULTRAVIOLET-ABSORBING ACRYLIC COPOLYMER FOR THE PRODUCTION OF FLEXIBLE INTRAOCULAR LENS | Acrylian (FR) | 2023-07-26 | — | — | EP | disclosed |
| US-20210121325-A1 | METHODS AND COMPOSITIONS FOR IONTOPHORETIC DRUG DELIVERY TO THE EYE | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2021-04-29 | — | — | US | disclosed |
| US-10626206-B2 | Acrylic copolymer, which is hydrophobic, cross-linked and based on cinnamic alcohol, for intraocular lenses | ACRYLIAN (FR) | 2020-04-21 | — | — | US | disclosed |
| US-4056496-A | ACRYLIC | CORNEAL SCIENCES, INC. (US) | 1977-11-01 | — | — | US | disclosed |
| US-4056496-A | ACRYLIC | CORNEAL SCIENCES, INC. (US) | 1977-11-01 | — | — | US | disclosed |
| US-3957362-A | Hydrogels and articles made therefrom | CORNEAL SCIENCES, INC. (US) | 1976-05-18 | — | — | US | disclosed |
| US-3957362-A | Hydrogels and articles made therefrom | CORNEAL SCIENCES, INC. (US) | 1976-05-18 | — | — | US | disclosed |