SCHEMBL454373

SCHEMBL454373

CC(=O)[Si](C)(C(C)=O)C(C)=O

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.42
TSHR P16473 2/20 0.39
THPO P40225 1/20 0.39
FFAR3 O14843 1/20 0.39
LCK P06239 1/20 0.39
FYN P06241 1/20 0.39
CA1 P00915 2/20 0.36
ALOX15 P16050 1/20 0.36
BLM P54132 1/20 0.36
PMP22 Q01453 1/20 0.36
ALDH1A1 P00352 4/20 0.31
TDP1 Q9NUW8 1/20 0.31
KDM4E B2RXH2 1/20 0.31
CA2 P00918 1/20 0.31
PTGS1 P23219 1/20 0.31
MMP12 P39900 1/20 0.31
CA4 P22748 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL444840 0.76
SCHEMBL28346313 0.70
SCHEMBL4945129 0.67 LMNA (0.46) LMNATSHRTHPOFFAR3LCK
Acetic Acid SCHEMBL3392891 0.67
Acetic Acid SCHEMBL9623142 0.64
Acetic Acid SCHEMBL3836837 0.64 FFAR3 (0.64) LMNATSHRTHPOFFAR3LCK
Acetic Acid SCHEMBL21518270 0.64
Acetone SCHEMBL29111176 0.64
Acetone SCHEMBL662 0.61
Acetone SCHEMBL8041527 0.61 LMNA (1.00) LMNATSHRTHPOFFAR3LCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119736062-B Preparation method of ethyl-dehydrolactoate-type silicone sealant 山东永安胶业有限公司 2025-06-03 CN claimed
CN-119736062-A Preparation method of ethyl-dehydrolactoate-type silicone sealant 山东永安胶业有限公司 2025-04-01 CN claimed
CN-117659936-A Preparation method of environment-friendly super-strong mildew-proof matte de-esterification type beautifying and edge-finishing sealant 山东沃赛新材料科技有限公司 2024-03-08 CN claimed
US-11814573-B2 Thermoplastic elastomer for profile control and water shutoff and method for preparing same UNIV SOUTHWEST PETROLEUM (CN) 2023-11-14 US claimed
CN-116712757-A Organic silicon composition and preparation method thereof 江苏四新科技应用研究所股份有限公司 2023-09-08 CN claimed
US-20220089935-A1 THERMOPLASTIC ELASTOMER FOR PROFILE CONTROL AND WATER SHUTOFF AND METHOD FOR PREPARING SAME UNIV SOUTHWEST PETROLEUM (CN) 2022-03-24 US claimed
US-20130072647-A1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF PETROCHINA COMPANY LIMITED (CN) 2013-03-21 US claimed
EP-2567986-A1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF Petrochina Company Limited (CN) 2013-03-13 EP claimed
CN-102746426-A Olefin polymerization catalyst, preparation and application thereof PETROCHINA CO LTD 2012-10-24 CN claimed
EP-1306391-B1 Ziegler-Natta catalyst for tuning MWD of polyolefin, method of making, method of using and polyolefins made therewith TOTAL PETROCHEMICALS RES FELUY (BE) 2008-04-30 EP claimed
US-6734134-B1 TREATING A MAGNESIUM DIALKOXIDE WITH TWO HALOGENATING/TITANATING AGENTS, THE SECOND STRONGER THAN THE FIRST, THEN AN ORGANOALUMINUM PREACTIVATING AGENT, HEAT TREATING FINA TECHNOLOGY, INC. 2004-05-11 US claimed
EP-0855409-B1 Improved Ziegler-Natta catalysts for olefin polymerization FINA TECHNOLOGY (US) 2004-04-28 EP claimed
EP-1306391-A1 Ziegler-Natta catalyst for tuning MWD of polyolefin, method of making, method of using and polyolefins made therewith FINA TECHNOLOGY, INC. (US) 2003-05-02 EP claimed
US-6174971-B1 POLYMERIZATION CATALYSTS OF ALUMINUM AND MAGNESIUM COMPOUNDS FINA TECHNOLOGY, INC. 2001-01-16 US claimed
EP-0855409-A1 Improved Ziegler-Natta catalysts for olefin polymerization FINA TECHNOLOGY, INC. (US) 1998-07-29 EP claimed
CN-113933132-B Muscle specimen preservation method based on plasticizing specimen muscle stain 河南中博科技有限公司 2024-03-12 CN disclosed
WO-2023218890-A1 COMPOSITION, COMPOUND, SURFACE TREATMENT AGENT, ARTICLE, AND METHOD FOR PRODUCING ARTICLE AGC株式会社 2023-11-16 WO disclosed
US-4781973-A WATERPROOF, OIL REPELLANT AND ANTISOILANT POLYSILOXANE GENERAL ELECTRIC COMPANY (US) 1988-11-01 US disclosed
EP-0275378-A1 Water repellent for masonry GENERAL ELECTRIC COMPANY (US) 1988-07-27 EP disclosed
US-4753977-A POLYSILOXANE RESINS, CROSSLINKING, CURABLE BLENDS; CATALYST GENERAL ELECTRIC COMPANY (US) 1988-06-28 US disclosed