SCHEMBL444840

SCHEMBL444840

CC(=O)[Si](C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28941779 0.82 LMNA (0.31)
SCHEMBL454373 0.76 LMNA (0.42)
SCHEMBL28346313 0.73
Acetone SCHEMBL490180 0.72
Acetone SCHEMBL6755062 0.72
SCHEMBL23879189 0.70
SCHEMBL28220095 0.70 LMNA (0.33)
Acetic Acid SCHEMBL3392891 0.70
SCHEMBL1101045 0.70
SCHEMBL4945129 0.70 LMNA (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116041835-B High-strength heat-shrinkable sleeve material, high-strength heat-shrinkable sleeve and application thereof 深圳市东霖科技有限公司 2024-11-22 CN claimed
CN-117944154-A Release agent for artificial stone 常州绿之源高分子材料有限公司 2024-04-30 CN claimed
CN-112340749-B Preparation method and application of organic functional group functionalized MCM molecular sieve 中国石油化工股份有限公司 2023-10-13 CN claimed
CN-116041835-A High-strength heat-shrinkable sleeve material, high-strength heat-shrinkable sleeve and application thereof 深圳市东霖科技有限公司 2023-05-02 CN claimed
CN-113640435-A Alternaria alternata toxin LC-MSMS rapid quantitative detection method 上海市农产品质量安全中心 2021-11-12 CN claimed
CN-102189627-B Mould release agent and preparation method thereof and application of mould release agent in preparation of polyurethane mould product BI JIANGUANG 2014-06-04 CN claimed
JP-2234977-A None JP disclosed
EP-4658657-A1 SUBSTITUTED TRICYCLIC COMPOUNDS Mirati Therapeutics, Inc. (US) 2025-12-10 EP disclosed
US-12428421-B2 Pyrimidinones as factor XIA inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2025-09-30 US disclosed
CN-116041835-B High-strength heat-shrinkable sleeve material, high-strength heat-shrinkable sleeve and application thereof 深圳市东霖科技有限公司 2024-11-22 CN disclosed
CN-114096542-B Condensed tricyclic pyrroles as alpha-1 antitrypsin modulators 弗特克斯药品有限公司 2024-09-10 CN disclosed
CN-118510780-A Spiro heterocyclic compounds and uses thereof 广州必贝特医药股份有限公司 2024-08-16 CN disclosed
WO-2024163707-A1 SUBSTITUTED TRICYCLIC COMPOUNDS Mirati Therapeutics, Inc. (US) 2024-08-08 WO disclosed
US-6037001-A Method for the chemical vapor deposition of copper-based films GELEST, INC. (US) 2000-03-14 US disclosed
EP-0839869-A2 Silicone rubber composition Dow Corning Toray Silicone Company, Limited (JP) 1998-05-06 EP disclosed
EP-0478780-B1 METHOD AND DEVICE FOR DETERMINING FIELD OF PRESSURE OF CONTINUOUS FLUID MEDIUM ON THE SURFACE OF AN OBJECT TS AEROGIDRODINAMICHESKY I IM (RU) 1995-01-18 EP disclosed
EP-0478780-A1 METHOD AND DEVICE FOR DETERMINING FIELD OF PRESSURE OF CONTINUOUS FLUID MEDIUM ON THE SURFACE OF AN OBJECT TSENTRALNY AEROGIDRODINAMICHESKY INSTITUT IMENI N.E. ZHUKOVSKOGO (RU) 1992-04-08 EP disclosed
JP-H02234977-A CLOTH HAVING WATER-REPELLENCY TORAY IND INC 1990-09-18 JP disclosed
US-4536336-A New anthracyclinones and their production MEIJI SEIKA KAISHA, LTD. (JP) 1985-08-20 US disclosed
EP-0114001-A1 New anthracyclinones and their production MEIJI SEIKA KAISHA LTD. (JP) 1984-07-25 EP disclosed