Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HBB | P68871 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SLC27A1 | Q6PCB7 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4542422 | 0.99 | LMNA (0.40) | LMNASMN1; SMN2MEN1KMT2AHBB | |
| SCHEMBL1849172 | 0.92 | TNF (0.37) | LMNASMN1; SMN2MEN1KMT2AHBB | |
| SCHEMBL1842060 | 0.91 | TNF (0.37) | LMNASMN1; SMN2MEN1KMT2AHBB | |
| SCHEMBL1846424 | 0.91 | ACVR1B (0.44) | SMN1; SMN2ACHEP2RX7NPC1RAB9A | |
| SCHEMBL1846451 | 0.89 | PIK3CA (0.45) | ABL1ALDH1A1CNR2 | |
| SCHEMBL1844044 | 0.89 | HDAC2 (0.45) | SMN1; SMN2NPC1RAB9AABL1ACVR1B | |
| SCHEMBL1840483 | 0.89 | ABL1 (0.37) | ABL1CNR2 | |
| Hydrochloric Acid SCHEMBL1841930 | 0.88 | ABL1 (0.36) | ABL1CNR2 | |
| Hydrochloric Acid SCHEMBL1843751 | 0.87 | ACHE (0.43) | LMNASMN1; SMN2MEN1KMT2AHBB | |
| Lithium Ion SCHEMBL1842051 | 0.85 | ACHE (0.36) | LMNASMN1; SMN2MEN1KMT2AHBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009156966-A1 | BENZOTHIAZOLES AND AZA-ANALOGUES THEREOF USE AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2009-12-30 | — | — | WO | disclosed |