Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18191 | 0.86 | CYP2C19 (0.42) | CYP2C19 | |
| Methylene Chloride SCHEMBL3565257 | 0.83 | CYP2C19 (0.36) | CYP2C19 | |
| SCHEMBL28557000 | 0.82 | CYP2C19 (0.40) | CYP2C19 | |
| Hydrochloric Acid SCHEMBL8858515 | 0.82 | CYP2C19 (0.40) | CYP2C19 | |
| Methyl Alcohol SCHEMBL4271767 | 0.79 | CYP2C19 (0.38) | CYP2C19 | |
| Ethylene SCHEMBL4765785 | 0.79 | CYP2C19 (0.38) | CYP2C19 | |
| Fluoride SCHEMBL15313130 | 0.79 | CYP2C19 (0.38) | CYP2C19 | |
| Fluoride SCHEMBL732880 | 0.79 | CYP2C19 (0.38) | CYP2C19 | |
| Methylene Chloride SCHEMBL3581296 | 0.78 | CYP2C19 (0.33) | CYP2C19 | |
| Isopropylamine SCHEMBL8865306 | 0.78 | CYP2C19 (0.33) | CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240199620-A1 | CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF | RAPT THERAPEUTICS, INC. | 2024-06-20 | — | — | US | disclosed |
| EP-3490565-B1 | AZETIDINE DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF | RAPT THERAPEUTICS INC (US) | 2022-06-08 | — | — | EP | disclosed |
| US-20200239480-A1 | CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF | RAPT THERAPEUTICS INC (US) | 2020-07-30 | — | — | US | disclosed |
| US-10604526-B2 | Chemokine receptor modulators and uses thereof | RAPT THERAPEUTICS, INC. (US) | 2020-03-31 | — | — | US | disclosed |
| EP-3490565-A1 | CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF | FLX Bio, Inc. (US) | 2019-06-05 | — | — | EP | disclosed |
| US-20190152978-A1 | CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF | RAPT THERAPEUTICS, INC. | 2019-05-23 | — | — | US | disclosed |
| US-10179787-B2 | Chemokine receptor modulators and uses thereof | FLX BIO, INC. (US) | 2019-01-15 | — | — | US | disclosed |
| US-20180072740-A1 | CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF | RAPT THERAPEUTICS, INC. | 2018-03-15 | — | — | US | disclosed |
| WO-2018022992-A1 | CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF | FLX BIO, INC. (US) | 2018-02-01 | — | — | WO | disclosed |
| US-20090069448-A1 | Degradable polymer and process for production thereof | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2009-03-12 | — | — | US | disclosed |
| US-7388095-B2 | 5-substituted indole-2-carboxamide derivatives | HOFFMANN-LA ROCHE INC. (US) | 2008-06-17 | — | — | US | disclosed |
| EP-1897898-A1 | DEGRADABLE POLYMER AND PROCESS FOR PRODUCTION THEREOF | Japan Science and Technology Agency (JP) | 2008-03-12 | — | — | EP | disclosed |
| US-20070123525-A1 | 5-Substituted indole-2-carboxamide derivatives | HOFFMANN-LA ROCHE INC. | 2007-05-31 | — | — | US | disclosed |
| US-5541187-A | HYPOTENSIVE AGENTS | STERLING WINTHROP INC. (US) | 1996-07-30 | — | — | US | disclosed |
| US-5294612-A | Hypotensive agents and cardiovascular disorders | STERLING WINTHROP INC. (US) | 1994-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190152978-A1 | CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF | CCR4, CCR1, CCR3 | CYP2C19 3628/4885 |
| US-10604526-B2 | Chemokine receptor modulators and uses thereof | CCR4, CCR1, CCR3 | CYP2C19 3628/4885 |
| US-20200239480-A1 | CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF | CCR4, CCR1, CCR3 | CYP2C19 3628/4885 |
| US-20090069448-A1 | Degradable polymer and process for production thereof | HPGDS, PPOX, HCCS | CYP2C19 168/4885 |
| US-20070123525-A1 | 5-Substituted indole-2-carboxamide derivatives | HRH4, HRH3, HCAR2 | CYP2C19 536/4885 |
| US-20180072740-A1 | CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF | CCR4, CCR1, CCR3 | CYP2C19 3628/4885 |
| US-20240199620-A1 | CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF | CCR4, CCR1, CCR3 | CYP2C19 3628/4885 |
| US-10179787-B2 | Chemokine receptor modulators and uses thereof | CCR4, CCR1, CCR3 | CYP2C19 3628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.