Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGPAT2 | O15120 | 7/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
| ▸ | CCR8 | P51685 | 1/20 | 0.30 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1025362 | 0.83 | S1PR1 (0.35) | AGPAT2S1PR1 | |
| SCHEMBL4544443 | 0.80 | KDM4E (0.50) | AGPAT2ESR1ESR2 | |
| SCHEMBL4544542 | 0.77 | NPC1 (0.39) | AGPAT2ESR1ESR2CCR1CCR5 | |
| SCHEMBL1024021 | 0.74 | MAOB (0.36) | — | |
| SCHEMBL1026330 | 0.70 | AGPAT2 (0.49) | AGPAT2ESR1ESR2S1PR1 | |
| SCHEMBL4544510 | 0.69 | S1PR1 (0.41) | ESR1ESR2CCR1CCR5CCR8 | |
| SCHEMBL15426365 | 0.68 | ATR (0.42) | SGMS2 | |
| SCHEMBL4544470 | 0.68 | SGMS2 (0.40) | ESR1ESR2CCR1CCR5CCR8 | |
| SCHEMBL4544486 | 0.68 | NPC1 (0.35) | CCR1CCR5CCR8SGMS2S1PR1 | |
| SCHEMBL15426364 | 0.68 | SGMS2 (0.38) | SGMS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130190271-A1 | FUSED HETEROCYCLIC COMPOUNDS AND USES THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-07-25 | — | — | US | disclosed |
| US-8324387-B2 | Substituted Oxazolo[5,4-b]pyridines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-12-04 | — | — | US | disclosed |
| US-20120264750-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-18 | — | — | US | disclosed |
| US-20120245159-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-09-27 | — | — | US | disclosed |
| US-8242133-B2 | Arthropod pest control compositions comprising substituted oxazolo [5,4-b ] pyridines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-14 | — | — | US | disclosed |
| US-20120108586-A1 | ARTHROPOD PEST CONTROL METHOD AND COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108586-A1 | ARTHROPOD PEST CONTROL METHOD AND COMPOSITION | C5, C1S, C1R | AGPAT2 652/4885ESR1 3274/4885ESR2 2840/4885 |
| US-20120264750-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | DDT, ACHE, AADAC | AGPAT2 1499/4885ESR1 4830/4885ESR2 4739/4885 |
| US-20120245159-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | NISCH, DDT, AADAC | AGPAT2 2123/4885ESR1 4496/4885ESR2 4454/4885 |
| US-20130190271-A1 | FUSED HETEROCYCLIC COMPOUNDS AND USES THEREOF | CYC1, C9, C5 | AGPAT2 1407/4885ESR1 1513/4885ESR2 1544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.