SCHEMBL4544722

SCHEMBL4544722

CCCCN(C=CC=C1C(=O)CC(C)(C)CC1=O)CCCC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.39
HTT P42858 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.36
POLB P06746 2/20 0.36
TP53 P04637 1/20 0.36
CTDSP1 Q9GZU7 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ALDH1A1 P00352 6/20 0.35
THRB P10828 1/20 0.35
MAPT P10636 4/20 0.35
NPSR1 Q6W5P4 2/20 0.33
KDM4E B2RXH2 1/20 0.30
GAA P10253 1/20 0.30
HPGD P15428 1/20 0.30
PTGES O14684 2/20 0.30
ALOX5 P09917 2/20 0.30
ALPL P05186 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19240037 0.94 ALDH1A1 (0.39) APPSMN1; SMN2HTTL3MBTL1POLB
SCHEMBL19240028 0.84 APP (0.44) APPSMN1; SMN2HTTL3MBTL1POLB
SCHEMBL12758233 0.78 APP (0.43) APPSMN1; SMN2HTTL3MBTL1POLB
SCHEMBL12260820 0.76 APP (0.41) APPSMN1; SMN2L3MBTL1POLBTP53
SCHEMBL9889234 0.76 APP (0.41) APPSMN1; SMN2HTTL3MBTL1POLB
SCHEMBL12310447 0.76 APP (0.41) APPSMN1; SMN2L3MBTL1POLBTP53
SCHEMBL13855924 0.75 POLB (0.61) APPSMN1; SMN2HTTL3MBTL1POLB
SCHEMBL10098421 0.75 POLB (0.61) APPSMN1; SMN2HTTL3MBTL1POLB
SCHEMBL12758232 0.72 PTPN1 (0.43) APPL3MBTL1POLBTDP1MEN1
SCHEMBL12758250 0.68 PTGS1 (0.35) SMN1; SMN2L3MBTL1POLBTP53CTDSP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178601-B2 Polymer film, polarizing plate protective film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-20090080074-A1 POLYMER FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-03-26 US disclosed
US-20080204644-A1 Liquid crystal display device FUJIFILM CORPORATION (JP) 2008-08-28 US disclosed
US-20080192192-A1 Optical film and polarizing plate FUJIFILM CORPORATION (JP) 2008-08-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090080074-A1 POLYMER FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE RPA3, RTF1, RPA1 APP 1275/4885SMN1; SMN2 3431/4885HTT 3261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.