Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 1.00 |
| ▸ | HMGCR | P04035 | 6/20 | 1.00 |
| ▸ | LMNA | P02545 | 5/20 | 1.00 |
| ▸ | TSHR | P16473 | 5/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | ABCB11 | O95342 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | MTOR | P42345 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 1.00 |
| ▸ | GMNN | O75496 | 1/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 1/20 | 1.00 |
| ▸ | BLM | P54132 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mevastatin SCHEMBL14545225 | 1.00 | CYP3A4 (1.00) | CYP3A4HMGCRLMNATSHRSMN1; SMN2 | |
| Mevastatin SCHEMBL15976637 | 1.00 | CYP3A4 (1.00) | CYP3A4HMGCRLMNATSHRSMN1; SMN2 | |
| Mevastatin SCHEMBL14307237 | 1.00 | CYP3A4 (1.00) | CYP3A4HMGCRLMNATSHRSMN1; SMN2 | |
| Mevastatin SCHEMBL23936978 | 1.00 | CYP3A4 (1.00) | CYP3A4HMGCRLMNATSHRSMN1; SMN2 | |
| Mevastatin SCHEMBL7721400 | 1.00 | CYP3A4 (1.00) | CYP3A4HMGCRLMNATSHRSMN1; SMN2 | |
| Mevastatin SCHEMBL23636208 | 1.00 | CYP3A4 (1.00) | CYP3A4HMGCRLMNATSHRSMN1; SMN2 | |
| Mevastatin SCHEMBL21340588 | 1.00 | CYP3A4 (1.00) | CYP3A4HMGCRLMNATSHRSMN1; SMN2 | |
| Mevastatin SCHEMBL21340571 | 1.00 | CYP3A4 (1.00) | CYP3A4HMGCRLMNATSHRSMN1; SMN2 | |
| Mevastatin SCHEMBL21340628 | 1.00 | CYP3A4 (1.00) | CYP3A4HMGCRLMNATSHRSMN1; SMN2 | |
| Mevastatin SCHEMBL14544858 | 1.00 | CYP3A4 (1.00) | CYP3A4HMGCRLMNATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108536-A1 | PHARMACEUTICAL COMPOSITION AND METHOD FOR INHIBITING INFLAMMATION | CHINA MEDICAL UNIVERSITY (TW) | 2012-05-03 | — | — | US | disclosed |
| US-20120108536-A1 | PHARMACEUTICAL COMPOSITION AND METHOD FOR INHIBITING INFLAMMATION | CHINA MEDICAL UNIVERSITY (TW) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108536-A1 | PHARMACEUTICAL COMPOSITION AND METHOD FOR INHIBITING INFLAMMATION | HMGCR, HMGB2, HMGB3 | CYP3A4 617/4885HMGCR 1/4885LMNA 1874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.