SCHEMBL4544800

SCHEMBL4544800

COC(=O)C(C)=CC=CN(C)C

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
GAA P10253 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
MAPT P10636 3/20 0.49
KDM4E B2RXH2 2/20 0.49
CYP2C9 P11712 1/20 0.49
DNMT1 P26358 1/20 0.49
CYP2C19 P33261 1/20 0.49
RECQL P46063 1/20 0.49
ALDH1A1 P00352 3/20 0.34
APP P05067 1/20 0.32
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13412686 0.81 MAPT (0.50) POLBMEN1KMT2AGAATDP1
SCHEMBL14095057 0.81 MAPT (0.50) POLBMEN1KMT2AGAATDP1
SCHEMBL8582235 0.80 ALDH1A1 (0.42) POLBMEN1KMT2AGAATDP1
SCHEMBL8582231 0.80 ALDH1A1 (0.42) POLBMEN1KMT2AGAATDP1
SCHEMBL9393810 0.78 POLB (0.39) POLBMEN1KMT2AGAATDP1
SCHEMBL13855931 0.78 POLB (0.39) POLBMEN1KMT2AGAATDP1
SCHEMBL14095049 0.78 POLB (0.39) POLBMEN1KMT2AGAATDP1
SCHEMBL25246818 0.77 ALDH1A1 (0.48) POLBMEN1KMT2AGAATDP1
SCHEMBL7343451 0.76 ALDH1A1 (0.39) POLBMEN1KMT2AGAATDP1
SCHEMBL11252127 0.76 ALDH1A1 (0.39) POLBMEN1KMT2AGAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178601-B2 Polymer film, polarizing plate protective film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-20090080074-A1 POLYMER FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-03-26 US disclosed
US-20080204644-A1 Liquid crystal display device FUJIFILM CORPORATION (JP) 2008-08-28 US disclosed
US-20080192192-A1 Optical film and polarizing plate FUJIFILM CORPORATION (JP) 2008-08-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090080074-A1 POLYMER FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE RPA3, RTF1, RPA1 POLB 1081/4885MEN1 2012/4885KMT2A 3282/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.