Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45448 | 0.85 | TRPV1 (0.45) | TRPV1TRPA1RPS6KA3MAPTGSK3A | |
| SCHEMBL44829 | 0.83 | TRPV1 (0.43) | TRPV1TRPA1RPS6KA3MAPTGSK3A | |
| SCHEMBL16014860 | 0.78 | KDM4E (0.44) | TRPV1TRPA1MAPT | |
| SCHEMBL44846 | 0.78 | TRPV1 (0.50) | TRPV1TRPA1 | |
| SCHEMBL16014859 | 0.73 | TRPA1 (0.41) | TRPV1TRPA1 | |
| SCHEMBL16014572 | 0.72 | TRPA1 (0.37) | TRPV1TRPA1 | |
| SCHEMBL16014772 | 0.72 | SLC16A3 (0.38) | TRPV1TRPA1 | |
| SCHEMBL45196 | 0.72 | OPRL1 (0.37) | TRPV1TRPA1 | |
| SCHEMBL9995913 | 0.71 | TRPA1 (0.38) | TRPV1TRPA1 | |
| SCHEMBL45356 | 0.71 | TRPA1 (0.42) | TRPV1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582688-B1 | ANTHRANILIC ACID DIAMIDE DERIVATIVES | BAYER IP GMBH (DE) | 2015-10-07 | — | — | EP | disclosed |
| EP-2582688-A1 | ANTHRANILIC ACID DIAMIDE DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2013-04-24 | — | — | EP | disclosed |
| WO-2011157654-A1 | ANTHRANILIC ACID DIAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2011-12-22 | — | — | WO | disclosed |