Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 12/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44847 | 0.83 | TRPV1 (0.53) | TRPV1TRPA1PTGS1EPHX2PTGS2 | |
| SCHEMBL16014860 | 0.79 | KDM4E (0.44) | TRPV1TRPA1 | |
| SCHEMBL45449 | 0.78 | TRPV1 (0.43) | TRPV1TRPA1 | |
| SCHEMBL45196 | 0.76 | OPRL1 (0.37) | TRPV1TRPA1 | |
| SCHEMBL45281 | 0.74 | TRPA1 (0.35) | TRPV1TRPA1 | |
| SCHEMBL10118252 | 0.73 | TRPV1 (0.43) | TRPV1NPY5R | |
| SCHEMBL10118261 | 0.73 | TRPV1 (0.45) | TRPV1NPY5R | |
| SCHEMBL16014859 | 0.73 | TRPA1 (0.41) | TRPV1TRPA1 | |
| SCHEMBL16014772 | 0.73 | SLC16A3 (0.38) | TRPV1TRPA1 | |
| SCHEMBL16014572 | 0.73 | TRPA1 (0.37) | TRPV1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582688-A1 | ANTHRANILIC ACID DIAMIDE DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2013-04-24 | — | — | EP | disclosed |
| WO-2011157654-A1 | ANTHRANILIC ACID DIAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2011-12-22 | — | — | WO | disclosed |