Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 3/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 7/20 | 0.39 |
| ▸ | CES1 | P23141 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4544980 | 1.00 | TSHR (0.46) | TSHRCES2NAAAHCAR2RAD52 | |
| SCHEMBL4544971 | 1.00 | TSHR (0.46) | TSHRCES2NAAAHCAR2RAD52 | |
| SCHEMBL4544977 | 1.00 | TSHR (0.46) | TSHRCES2NAAAHCAR2RAD52 | |
| SCHEMBL4544972 | 1.00 | TSHR (0.46) | TSHRCES2NAAAHCAR2RAD52 | |
| SCHEMBL4544974 | 0.87 | HCAR2 (0.34) | CES2HCAR2CES1ALDH1A1 | |
| SCHEMBL4544960 | 0.83 | TSHR (0.54) | TSHRCES2NAAAHCAR2RAD52 | |
| SCHEMBL4544970 | 0.83 | TSHR (0.54) | TSHRCES2NAAAHCAR2RAD52 | |
| SCHEMBL4544985 | 0.83 | TSHR (0.50) | TSHRNAAAHCAR2RAD52NPSR1 | |
| SCHEMBL4544995 | 0.82 | S1PR1 (0.48) | TSHR | |
| SCHEMBL4544956 | 0.81 | TSHR (0.51) | TSHRCES2NAAAHCAR2RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8298736-B2 | Electrophotographic toner | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2012-10-30 | — | — | US | disclosed |
| US-8178267-B2 | Electrophotographic toner | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2012-05-15 | — | — | US | disclosed |
| US-20090291381-A1 | ELECTROPHOTOGRAPHIC TONER | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2009-11-26 | — | — | US | disclosed |
| US-20090291377-A1 | ELECTROPHOTOGRAPHIC TONER | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2009-11-26 | — | — | US | disclosed |
| US-20090233207-A1 | PYRAZOLOTRIAZOLE COMPOUND AND ELECTROPHOTOGRAPHIC TONER | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233207-A1 | PYRAZOLOTRIAZOLE COMPOUND AND ELECTROPHOTOGRAPHIC TONER | HAX1, XDH, GLRX3 | TSHR 254/4885CES2 2310/4885NAAA 3081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.