Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4545006 | 0.90 | BCHE (0.39) | ACHEBCHEALDH1A1MC4RL3MBTL1 | |
| SCHEMBL12018213 | 0.89 | BCHE (0.45) | ACHEBCHEALDH1A1SIGMAR1L3MBTL1 | |
| SCHEMBL11886646 | 0.83 | CA1 (0.44) | ACHEALDH1A1MC4RL3MBTL1CA1 | |
| SCHEMBL10245022 | 0.83 | CA1 (0.44) | ACHEALDH1A1MC4RL3MBTL1CA1 | |
| SCHEMBL1132754 | 0.81 | TAAR1 (0.41) | ACHEALDH1A1MC4RL3MBTL1CA1 | |
| SCHEMBL12608137 | 0.81 | ALDH1A1 (0.48) | ACHEBCHEALDH1A1MC4RSIGMAR1 | |
| SCHEMBL334590 | 0.81 | MC4R (0.38) | ACHEBCHEALDH1A1MC4RL3MBTL1 | |
| SCHEMBL334589 | 0.81 | MC4R (0.38) | ACHEBCHEALDH1A1MC4RL3MBTL1 | |
| SCHEMBL334999 | 0.81 | TAAR1 (0.41) | ACHEALDH1A1MC4RL3MBTL1CA1 | |
| SCHEMBL12608991 | 0.79 | MC4R (0.40) | ACHEALDH1A1MC4RHTR7CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120216867-A1 | FULLERENE DERIVATIVES | NATIONAL UNIVERSITY CORPORATION TOTTORI UNIVERSITY (JP) | 2012-08-30 | — | — | US | disclosed |
| US-20120111411-A1 | FULLERENE DERIVATIVE | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120111411-A1 | FULLERENE DERIVATIVE | HCN2, KCNN2, TMEM109 | ACHE 2879/4885BCHE 4202/4885ALDH1A1 1309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.