Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 8/20 | 0.41 |
| ▸ | ESR1 | P03372 | 7/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.37 |
| ▸ | GEMIN4 | P57678 | 1/20 | 0.37 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13311725 | 0.88 | APP (0.37) | ESR2ESR1GEMIN4HSF1NPC1 | |
| SCHEMBL23571947 | 0.70 | APP (0.37) | MAPTBACE1CA4CA1CA2 | |
| SCHEMBL29586904 | 0.68 | MAPT (0.47) | ESR2ESR1GEMIN4HSF1NPC1 | |
| SCHEMBL22220312 | 0.67 | BACE1 (0.68) | ESR2ESR1NPC1MAPTBACE1 | |
| SCHEMBL5890294 | 0.67 | NQO1 (0.62) | ESR2ESR1NPC1MAPTRAB9A | |
| SCHEMBL11921338 | 0.66 | ESR1 (0.47) | ESR2ESR1HSD17B1NPC1MAPT | |
| SCHEMBL28032825 | 0.65 | CES2 (0.49) | ESR2ESR1TTR | |
| SCHEMBL22789629 | 0.64 | APP (0.37) | ESR2ESR1MAPTNPSR1BACE1 | |
| SCHEMBL26346332 | 0.64 | HSD17B1 (0.47) | ESR2ESR1HSD17B1CA4CA1 | |
| SCHEMBL4179706 | 0.63 | PBRM1 (0.44) | ESR2HSD17B1MAPTCYP3A4TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8716191-B2 | Method of preparing an adduct | UNIVERSITE DE STRASBOURG (FR) | 2014-05-06 | — | — | US | disclosed |
| US-8716191-B2 | Method of preparing an adduct | UNIVERSITE DE STRASBOURG (FR) | 2014-05-06 | — | — | US | disclosed |
| EP-2446033-B1 | METHOD OF PREPARING AN ADDUCT | UNIV STRASBOURG (FR) | 2013-10-23 | — | — | EP | disclosed |
| US-20120115751-A1 | METHOD OF PREPARING AN ADDUCT | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-05-10 | — | — | US | disclosed |
| US-20120115751-A1 | METHOD OF PREPARING AN ADDUCT | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-05-10 | — | — | US | disclosed |
| WO-2010150103-A2 | METHOD OF PREPARING AN ADDUCT | UNIVERSITE DE STRASBOURG (FR) | 2010-12-29 | — | — | WO | disclosed |