SCHEMBL4545232

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL26054075	0.95	HPRT1 (0.41)	ALDH1A1KDM4EMAPTHPGDMEN1
	SCHEMBL25786213	0.95	GSTP1 (0.43)	ALDH1A1KDM4EMAPTHPGDGSTP1
	SCHEMBL17933153	0.94	MCL1 (0.37)	ALDH1A1KDM4EMAPTHPGDMEN1
	SCHEMBL22671846	0.92	CYP11B1 (0.41)	ALDH1A1KDM4EMAPTHPGDMEN1
	SCHEMBL26053436	0.91	HPRT1 (0.40)	ALDH1A1KDM4EMAPTHPGDMEN1
	SCHEMBL17933154	0.90	MCL1 (0.37)	ALDH1A1KDM4EMAPTHPGDMEN1
	SCHEMBL26054076	0.89	HPRT1 (0.36)	ALDH1A1KDM4EMAPTHPGDMEN1
	SCHEMBL24154049	0.89	CYP11B1 (0.41)	ALDH1A1KDM4EMAPTHPGDMEN1
	SCHEMBL8737540	0.89	CYP11B1 (0.42)	ALDH1A1KDM4EMAPTHPGDMEN1
	SCHEMBL9888990	0.89	HPRT1 (0.47)	ALDH1A1KDM4EMAPTHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.