Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 20/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 14/20 | 0.57 |
| ▸ | SLC6A5 | Q9Y345 | 11/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4545284 | 0.99 | SLC6A9 (0.56) | SLC6A9KCNH2SLC6A5CYP3A4CYP2D6 | |
| SCHEMBL1000046 | 0.99 | SLC6A9 (0.58) | SLC6A9KCNH2SLC6A5CYP3A4CYP2D6 | |
| SCHEMBL4545295 | 0.89 | SLC6A9 (0.57) | SLC6A9KCNH2SLC6A5CYP3A4CYP2D6 | |
| SCHEMBL406301 | 0.87 | SLC6A9 (0.54) | SLC6A9KCNH2SLC6A5CYP3A4CYP2D6 | |
| SCHEMBL375545 | 0.85 | SLC6A9 (0.55) | SLC6A9KCNH2SLC6A5CYP3A4CYP2D6 | |
| SCHEMBL15116193 | 0.85 | SLC6A9 (0.54) | SLC6A9KCNH2SLC6A5CYP3A4CYP2D6 | |
| SCHEMBL15104861 | 0.84 | SLC6A9 (0.55) | SLC6A9KCNH2SLC6A5CYP3A4CYP2D6 | |
| SCHEMBL4545282 | 0.84 | SLC6A9 (0.39) | SLC6A9KCNH2SLC6A5CYP3A4 | |
| SCHEMBL15116166 | 0.84 | SLC6A9 (0.53) | SLC6A9KCNH2SLC6A5CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL15104721 | 0.83 | SLC6A9 (0.54) | SLC6A9KCNH2SLC6A5CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120116095-A1 | GLYCINE TRANSPORTER INHIBITORS | TAISHO PHARMACEUTICAL C0., LTD. (JP) | 2012-05-10 | — | — | US | disclosed |
| US-20120116095-A1 | GLYCINE TRANSPORTER INHIBITORS | TAISHO PHARMACEUTICAL C0., LTD. (JP) | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120116095-A1 | GLYCINE TRANSPORTER INHIBITORS | SLC6A5, SLC1A2, SLC18A2 | SLC6A9 5/4885KCNH2 1410/4885SLC6A5 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.