Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.67 |
| ▸ | MAOA | P21397 | 3/20 | 0.67 |
| ▸ | TYR | P14679 | 3/20 | 0.67 |
| ▸ | BACE1 | P56817 | 3/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.67 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.67 |
| ▸ | STAT3 | P40763 | 2/20 | 0.67 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.67 |
| ▸ | RELA | Q04206 | 2/20 | 0.67 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.67 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.67 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.67 |
| ▸ | MAOB | P27338 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11974564 | 0.88 | APP (0.67) | APPMAPTCYP2D6MAOATYR | |
| SCHEMBL13262284 | 0.87 | KMT2A (0.54) | APPMAPTCYP2D6MAOATYR | |
| SCHEMBL13707310 | 0.83 | CYP4F2 (0.51) | APPMAPTCYP2D6MAOATYR | |
| SCHEMBL14503242 | 0.82 | APP (0.59) | APPMAPTCYP2D6MAOATYR | |
| SCHEMBL14532896 | 0.82 | APP (0.59) | APPMAPTCYP2D6MAOATYR | |
| SCHEMBL13262296 | 0.82 | MAOB (0.64) | APPMAPTCYP2D6MAOATYR | |
| SCHEMBL6291968 | 0.80 | XDH (0.67) | APPMAPTCYP2D6MAOATYR | |
| Curcumin SCHEMBL17629818 | 0.80 | APP (1.00) | APPMAPTCYP2D6MAOATYR | |
| Curcumin SCHEMBL250984 | 0.80 | APP (1.00) | APPMAPTCYP2D6MAOATYR | |
| Curcumin SCHEMBL8336603 | 0.80 | APP (1.00) | APPMAPTCYP2D6MAOATYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012055010-A1 | MAPLE TREE-DERIVED PRODUCTS AND USES THEREOF | FÉDÉRATION DES PRODUCTEURS ACÉRICOLES DU QUÉBEC (CA) | 2012-05-03 | — | — | WO | disclosed |