⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4545338 | 0.71 | TSHR (0.30) | — | |
| SCHEMBL19492027 | 0.63 | TSHR (0.32) | — | |
| SCHEMBL13083122 | 0.60 | — | — | |
| SCHEMBL24969478 | 0.60 | — | — | |
| SCHEMBL20143562 | 0.60 | — | — | |
| SCHEMBL844857 | 0.59 | — | — | |
| SCHEMBL24042487 | 0.58 | FDPS (0.33) | — | |
| SCHEMBL23426256 | 0.56 | RIPK1 (0.37) | — | |
| SCHEMBL21925362 | 0.56 | TSHR (0.40) | — | |
| SCHEMBL135476 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389006-B2 | Pharmaceutical compositions of adsorbates of amorphous drug | BEND RESEARCH, INC. (US) | 2013-03-05 | — | — | US | disclosed |
| US-8197848-B2 | Pharmaceutical compositions of cholesteryl ester transfer protein inhibitors | BEND RESEARCH, INC. (US) | 2012-06-12 | — | — | US | disclosed |
| US-8173142-B2 | Pharmaceutical compositions of drugs and neutralized acidic polymers | BEND RESEARCH, INC. (US) | 2012-05-08 | — | — | US | disclosed |
| US-20090011024-A1 | Pharmaceutical compositions of dispersions of amorphous drugs mixed with polymers | PFIZER INC. | 2009-01-08 | — | — | US | disclosed |
| US-20080292707-A1 | Pharmaceutical Compositions of Adsorbates of Amorphous Drug | PFIZER INC | 2008-11-27 | — | — | US | disclosed |
| US-20070282009-A1 | Pharmaceutical compositions of cholesteryl ester transfer protein inhibitors | PFIZER INC | 2007-12-06 | — | — | US | disclosed |
| US-20070148236-A1 | Pharmaceutical Compositions of Adsorbates of Amorphous Drug | PFIZER PRODUCTS INC. | 2007-06-28 | — | — | US | disclosed |
| US-7235259-B2 | Pharmaceutical compositions of cholesteryl ester transfer protein inhibitors | PFIZER INC (US) | 2007-06-26 | — | — | US | disclosed |