SCHEMBL4546184

SCHEMBL4546184

Cc1cc(-c2ccc(Cl)cc2)cc(Cl)c1C1=C(O)C(C)(CCCO)NC1=O

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ACACB O00763 11/20 0.39
ACACA Q13085 11/20 0.39
GSK3B P49841 2/20 0.32
GSK3A P49840 1/20 0.32
CNR2 P34972 2/20 0.31
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4546186 0.88 ACACB (0.42) ACACBACACAGSK3BGSK3ARECQL
SCHEMBL4549943 0.87 ACACB (0.43) ACACBACACAGSK3BGSK3ARECQL
SCHEMBL4546188 0.83 ACACB (0.33) ACACBACACA
SCHEMBL4546194 0.82 ACACB (0.40) ACACBACACARECQL
SCHEMBL4546185 0.78 ACACB (0.50) ACACBACACAGSK3BGSK3ARECQL
SCHEMBL13817785 0.75 ACACB (0.42) ACACBACACAGSK3BGSK3ARECQL
SCHEMBL4546183 0.75 ACACB (0.47) ACACBACACAGSK3BGSK3ARECQL
SCHEMBL4546200 0.74 ACACB (0.46) ACACBACACACNR2RECQL
SCHEMBL12136952 0.73 ACACB (0.34) ACACBACACA
SCHEMBL4546193 0.72 ACACB (0.38) ACACBACACARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8173697-B2 Alkoxyalkyl-substituted cyclic keto-enols BAYER CROPSCIENCE AG (DE) 2012-05-08 US disclosed
US-20090298828-A1 Alkoxyalkyl-Substituted Cyclic Keto-Enols BAYER CROPSCIENCE AG (DE) 2009-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090298828-A1 Alkoxyalkyl-Substituted Cyclic Keto-Enols DDT, AKR1D1, EBP ACACB 249/4885ACACA 529/4885GSK3B 1247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.