SCHEMBL4546863

SCHEMBL4546863

Cc1cccc([Si](c2ccccc2)(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 5/20 0.50
TSHR P16473 2/20 0.46
LMNA P02545 1/20 0.46
ALOX12 P18054 1/20 0.46
NPSR1 Q6W5P4 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
HPGD P15428 1/20 0.42
ALDH1A1 P00352 1/20 0.41
MAPK1 P28482 1/20 0.41
ENPP3 O14638 1/20 0.38
KMT2A Q03164 1/20 0.38
TDP1 Q9NUW8 2/20 0.37
NQO2 P16083 1/20 0.37
TP53 P04637 1/20 0.37
ACP3 P15309 1/20 0.36
POLB P06746 1/20 0.36
ADORA2A P29274 1/20 0.36
ADORA1 P30542 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2454749 1.00 ACHE (0.50) ACHETSHRLMNAALOX12NPSR1
SCHEMBL2454956 1.00 ACHE (0.50) ACHETSHRLMNAALOX12NPSR1
SCHEMBL29265257 0.98 ACHE (0.48) ACHETSHRLMNAALOX12NPSR1
SCHEMBL25634961 0.94 ACHE (0.46) ACHETSHRLMNAALOX12NPSR1
SCHEMBL3241649 0.93 ACHE (0.58) ACHETSHRLMNAALOX12NPSR1
SCHEMBL20091265 0.92 ENPP3 (0.45) ACHETSHRLMNAALOX12NPSR1
SCHEMBL27430981 0.90 ENPP3 (0.47) ACHETSHRNPSR1SMN1; SMN2NPC1
SCHEMBL29265258 0.89 ACHE (0.44) ACHETSHRLMNAALOX12NPSR1
SCHEMBL25140387 0.88 ACHE (0.39) ACHETSHRLMNAALOX12NPSR1
SCHEMBL19849764 0.88 MEN1 (0.44) ACHETSHRLMNAALOX12NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240025927-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-25 US disclosed
US-20240025927-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-25 US disclosed
US-11844276-B2 Organic electroluminescent device emitting blue light SAMSUNG DISPLAY CO., LTD. (KR) 2023-12-12 US disclosed
US-20230389421-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-30 US disclosed
US-20230389421-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-30 US disclosed
US-20230363276-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-09 US disclosed
US-20230363276-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-09 US disclosed
US-20230329089-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-12 US disclosed
US-20230329089-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-12 US disclosed
WO-2023190159-A1 COMPOUND, LIGHT-EMITTING ELEMENT MATERIAL AND LIGHT-EMITTING ELEMENT OBTAINED USING SAME, PHOTOELECTRIC CONVERSION ELEMENT MATERIAL, COLOR CONVERSION COMPOSITION, COLOR CONVERSION SHEET, LIGHT SOURCE UNIT, DISPLAY DEVICE, AND LIGHTING DEVICE 東レ株式会社 2023-10-05 WO disclosed
US-20110204340-A1 ORGANIC LIGHT-EMITTING DIODE LUMINAIRES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-08-25 US disclosed
US-20110204339-A1 ORGANIC LIGHT-EMITTING DIODE LUMINAIRES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-08-25 US disclosed
US-20110204336-A1 ORGANIC LIGHT-EMITTING DIODE LUMINAIRES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-08-25 US disclosed
US-20110204337-A1 ORGANIC LIGHT-EMITTING DIODE LUMINAIRES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-08-25 US disclosed
US-20110147716-A1 OLED WITH HIGH EFFICIENCY BLUE LIGHT-EMITTING LAYER GLOBAL OLED TECHNOLOGY LLC 2011-06-23 US disclosed
US-20090236973-A1 ORGANIC COMPOUND, CHARGE-TRANSPORTING MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT PIONEER CORPORATION (JO) 2009-09-24 US disclosed
US-20090191426-A2 ORGANIC COMPOUND, CHARGE-TRANSPORTING MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT PIONEER CORPORATION (JP) 2009-07-30 US disclosed
US-20090165860-A1 Electroluminescent device using electroluminescent compounds GRACEL DISPLAY INC. (KR) 2009-07-02 US disclosed
US-20090078317-A1 Organometalic compounds for electroluminescence and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-03-26 US disclosed
US-20080145699-A1 Organic Compound, Charge-Transporting Material, and Organic Electroluminescent Element PIONEER CORPORATION (JP) 2008-06-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090078317-A1 Organometalic compounds for electroluminescence and organic electroluminescent device using the same OCIAD1, L1CAM, OCIAD2 ACHE 745/4885TSHR 4611/4885LMNA 1976/4885
US-20230363276-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ODC1 ACHE 253/4885TSHR 3696/4885LMNA 983/4885
US-20090191426-A2 ORGANIC COMPOUND, CHARGE-TRANSPORTING MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT SLC39A3, SLCO2A1, SLC39A11 ACHE 3305/4885TSHR 3892/4885LMNA 2784/4885
US-20230329089-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NR1H2, OXER1, NR1H3 ACHE 1062/4885TSHR 2232/4885LMNA 337/4885
US-20090236973-A1 ORGANIC COMPOUND, CHARGE-TRANSPORTING MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT SLCO4C1, SLCO2A1, SLCO2B1 ACHE 2219/4885TSHR 3924/4885LMNA 1605/4885
US-20240025927-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ODC1 ACHE 592/4885TSHR 3948/4885LMNA 2681/4885
US-20080145699-A1 Organic Compound, Charge-Transporting Material, and Organic Electroluminescent Element SLC39A3, SLCO2A1, SLC39A11 ACHE 3305/4885TSHR 3892/4885LMNA 2784/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.