Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4547654 | 0.78 | ABL1 (0.36) | — | |
| SCHEMBL4547656 | 0.77 | PPARA (0.43) | ACACB | |
| SCHEMBL4547652 | 0.73 | NFE2L2 (0.34) | — | |
| SCHEMBL11150281 | 0.73 | DBH (0.36) | ACACBDBH | |
| SCHEMBL13629737 | 0.73 | TSHR (0.32) | — | |
| SCHEMBL2467570 | 0.68 | DBH (0.41) | ACACBDBH | |
| SCHEMBL21503451 | 0.68 | DBH (0.41) | ACACBDBH | |
| SCHEMBL4603333 | 0.68 | TSHR (0.33) | — | |
| SCHEMBL586353 | 0.64 | HTR2A (0.39) | ACACBDBH | |
| SCHEMBL11146816 | 0.63 | DBH (0.38) | ACACBDBH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173704-B2 | Difluorophenol derivatives and their use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-05-08 | — | — | US | disclosed |
| US-20090291993-A1 | Difluorophenol Derivatives and Their Use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291993-A1 | Difluorophenol Derivatives and Their Use | TPMT, FABP3, DPP4 | ACACB 1331/4885DBH 747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.