Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 0.43 |
| ▸ | PPARD | Q03181 | 9/20 | 0.43 |
| ▸ | PPARG | P37231 | 9/20 | 0.39 |
| ▸ | PTGES | O14684 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | CPA3 | P15088 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4547653 | 0.77 | ACACB (0.32) | ACACB | |
| SCHEMBL22444755 | 0.74 | SLC7A5 (0.51) | PPARG | |
| SCHEMBL13629652 | 0.74 | CHRM1 (0.47) | PPARAPPARDPPARGPTGESALOX5 | |
| SCHEMBL29633874 | 0.71 | PPARD (0.42) | PPARAPPARDPPARGACACB | |
| SCHEMBL22444669 | 0.69 | GRIK1 (0.43) | — | |
| SCHEMBL2126253 | 0.68 | THRB (0.46) | PPARG | |
| SCHEMBL17019158 | 0.68 | STING1 (0.45) | PPARAPPARD | |
| SCHEMBL21503451 | 0.67 | DBH (0.41) | PPARAPPARDACACB | |
| SCHEMBL22444693 | 0.67 | ALDH1A1 (0.47) | PPARAPPARDACACB | |
| SCHEMBL29633824 | 0.67 | ACACB (0.38) | PPARAPPARDACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173704-B2 | Difluorophenol derivatives and their use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-05-08 | — | — | US | disclosed |