Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2675146 | 0.85 | CYP19A1 (0.31) | CYP19A1 | |
| SCHEMBL2675148 | 0.85 | CYP19A1 (0.31) | CYP19A1 | |
| SCHEMBL4603613 | 0.85 | CYP19A1 (0.31) | CYP19A1 | |
| SCHEMBL13629738 | 0.82 | MAPT (0.33) | MEN1ALDH1A1KMT2A | |
| SCHEMBL4547671 | 0.82 | CCR6 (0.39) | MEN1ALDH1A1KMT2A | |
| SCHEMBL4547673 | 0.81 | MMP12 (0.37) | CYP19A1MMP12MMP13 | |
| SCHEMBL4515111 | 0.80 | TAS2R14 (0.40) | MEN1ALDH1A1KMT2AMMP12MMP13 | |
| SCHEMBL4515115 | 0.80 | TAS2R14 (0.40) | MEN1ALDH1A1KMT2AMMP12MMP13 | |
| SCHEMBL2292822 | 0.78 | PRSS1 (0.40) | MEN1ALDH1A1KMT2AMMP12MMP13 | |
| SCHEMBL2295655 | 0.78 | PRSS1 (0.40) | MEN1ALDH1A1KMT2AMMP12MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173704-B2 | Difluorophenol derivatives and their use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-05-08 | — | — | US | disclosed |
| US-20090291993-A1 | Difluorophenol Derivatives and Their Use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291993-A1 | Difluorophenol Derivatives and Their Use | TPMT, FABP3, DPP4 | CYP19A1 784/4885MEN1 3679/4885ALDH1A1 168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.