SCHEMBL4549284

SCHEMBL4549284

c1cc(-c2cc3ccccc3c3ccccc23)cc(-c2cccc3c2sc2ccccc23)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.58
CYP11B1 P15538 1/20 0.43
PARP14 Q460N5 1/20 0.42
ALDH1A1 P00352 3/20 0.41
HPGD P15428 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
TSHR P16473 1/20 0.41
MAPK1 P28482 1/20 0.41
CASP1 P29466 1/20 0.41
HIF1A Q16665 1/20 0.41
HSD17B10 Q99714 1/20 0.41
PRKDC P78527 6/20 0.41
TNKS O95271 1/20 0.38
TNKS2 Q9H2K2 1/20 0.38
GPR3 P46089 1/20 0.38
MAPT P10636 3/20 0.38
PIK3CD O00329 2/20 0.36
PIK3CB P42338 2/20 0.36
BRD4 O60885 1/20 0.36
PIK3CA P42336 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2691143 0.98 ALOX5 (0.57) ALOX5CYP11B1PARP14ALDH1A1HPGD
SCHEMBL4549282 0.94 ALOX5 (0.57) ALOX5CYP11B1PARP14ALDH1A1HPGD
SCHEMBL896331 0.92 ALOX5 (0.60) ALOX5CYP11B1PARP14ALDH1A1HPGD
SCHEMBL4549279 0.91 ALOX5 (0.58) ALOX5CYP11B1PARP14ALDH1A1HPGD
SCHEMBL4549281 0.90 ALOX5 (0.58) ALOX5CYP11B1PARP14ALDH1A1HPGD
SCHEMBL19723348 0.90 ALOX5 (0.52) ALOX5CYP11B1PARP14ALDH1A1HPGD
SCHEMBL22889216 0.89 ALOX5 (0.48) ALOX5CYP11B1PARP14ALDH1A1HPGD
SCHEMBL12996531 0.89 ALOX5 (0.71) ALOX5PARP14ALDH1A1HPGDL3MBTL1
SCHEMBL22259690 0.89 ALOX5 (0.53) ALOX5CYP11B1PARP14ALDH1A1HPGD
SCHEMBL19271499 0.89 ALOX5 (0.51) ALOX5CYP11B1PARP14ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11380855-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-07-05 US disclosed
US-11063220-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2021-07-13 US disclosed
US-20200066999-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-02-27 US disclosed
US-9748503-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-08-29 US disclosed
US-9748503-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-08-29 US disclosed
US-9406889-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-08-02 US disclosed
US-9406889-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-08-02 US disclosed
US-20150171333-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-18 US disclosed
US-20150171333-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-18 US disclosed
US-20150076454-A1 PHOSPHORUS CONTAINING BIS(TRIDENATE) OSMIUM COMPLEXES UNIVERSAL DISPLAY CORPORATION (US) 2015-03-19 US disclosed
US-20150076454-A1 PHOSPHORUS CONTAINING BIS(TRIDENATE) OSMIUM COMPLEXES UNIVERSAL DISPLAY CORPORATION (US) 2015-03-19 US disclosed
US-8968888-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-03-03 US disclosed
US-8968888-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-03-03 US disclosed
US-20140367654-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2014-12-18 US disclosed
US-20140367654-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2014-12-18 US disclosed
US-20120104369-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-03 US disclosed
US-20120104369-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200066999-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP ALOX5 458/4885CYP11B1 1520/4885PARP14 618/4885
US-20120104369-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device MC1R, NR2E3, RPS19 ALOX5 3393/4885CYP11B1 286/4885PARP14 1234/4885
US-11380855-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, OSBP ALOX5 458/4885CYP11B1 1520/4885PARP14 618/4885
US-20150171333-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device MC1R, NR2E3, RPS19 ALOX5 3393/4885CYP11B1 286/4885PARP14 1234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.