SCHEMBL4549281

SCHEMBL4549281

c1ccc2c(c1)cc(-c1ccc3ccc(-c4cccc5c4sc4ccccc45)cc3c1)c1ccccc12

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.58
PRKDC P78527 2/20 0.41
S1PR5 Q9H228 10/20 0.40
S1PR4 O95977 8/20 0.40
PARP14 Q460N5 1/20 0.39
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38
CASP1 P29466 1/20 0.38
HIF1A Q16665 1/20 0.38
HSD17B10 Q99714 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CYP11B1 P15538 1/20 0.37
GPR84 Q9NQS5 1/20 0.36
GSTP1 P09211 1/20 0.36
MAPT P10636 1/20 0.35
GPR3 P46089 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL896331 0.91 ALOX5 (0.60) ALOX5PRKDCPARP14ALDH1A1HPGD
SCHEMBL15857005 0.90 ALOX5 (0.59) ALOX5PRKDCS1PR5S1PR4PARP14
SCHEMBL4549279 0.90 ALOX5 (0.58) ALOX5PRKDCPARP14ALDH1A1HPGD
SCHEMBL4549284 0.90 ALOX5 (0.58) ALOX5PRKDCPARP14ALDH1A1HPGD
SCHEMBL18086206 0.90 ALOX5 (0.66) ALOX5PRKDCS1PR5S1PR4PARP14
SCHEMBL16302997 0.90 ALOX5 (0.66) ALOX5PRKDCS1PR5S1PR4PARP14
SCHEMBL4549355 0.89 ALOX5 (0.52) ALOX5PRKDCS1PR5S1PR4PARP14
SCHEMBL2691143 0.89 ALOX5 (0.57) ALOX5PRKDCS1PR5S1PR4PARP14
SCHEMBL19723348 0.89 ALOX5 (0.52) ALOX5PRKDCS1PR5S1PR4PARP14
SCHEMBL17167404 0.88 ALOX5 (0.64) ALOX5PRKDCS1PR5S1PR4PARP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9406889-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-08-02 US disclosed
US-9406889-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-08-02 US disclosed
US-20150171333-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-18 US disclosed
US-20150171333-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-18 US disclosed
US-8968888-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-03-03 US disclosed
US-8968888-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-03-03 US disclosed
US-20120104369-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-03 US disclosed
US-20120104369-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120104369-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device MC1R, NR2E3, RPS19 ALOX5 3393/4885PRKDC 4132/4885S1PR5 4520/4885
US-20150171333-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device MC1R, NR2E3, RPS19 ALOX5 3393/4885PRKDC 4132/4885S1PR5 4520/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.