SCHEMBL4549304

SCHEMBL4549304

CCCc1ccc2sc3c(-c4ccc(-c5cc6ccccc6c6ccccc56)cc4)cc(CCC)cc3c2c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMB5 P28074 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
ATM Q13315 1/20 0.34
ALOX5 P09917 2/20 0.33
CNR1 P21554 2/20 0.33
CNR2 P34972 2/20 0.33
CYP11B1 P15538 1/20 0.33
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32
GAA P10253 1/20 0.32
KMT2A Q03164 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
RAB9A P51151 1/20 0.32
MAPT P10636 1/20 0.32
PIM1 P11309 2/20 0.31
PIM2 Q9P1W9 2/20 0.31
PIM3 Q86V86 1/20 0.31
PDE10A Q9Y233 1/20 0.31
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4549305 0.93 PSMB5 (0.43) PSMB5L3MBTL1ATMCNR2CYP11B1
SCHEMBL4549297 0.88 PIM1 (0.38) L3MBTL1ATMALOX5CYP11B1MEN1
SCHEMBL16541615 0.86
SCHEMBL4549310 0.82 DHODH (0.34) L3MBTL1ATMALOX5CNR1CNR2
SCHEMBL4549350 0.82 ALOX5 (0.47) PSMB5L3MBTL1ATMALOX5CNR1
SCHEMBL16541612 0.80 PSMB5 (0.34) PSMB5
SCHEMBL8281202 0.78 NPC1 (0.40) PSMB5MEN1POLBGAAKMT2A
SCHEMBL10127918 0.78 PTAFR (0.33) PSMB5L3MBTL1ATMKMT2AKDM4E
SCHEMBL4549289 0.78 GPR84 (0.37) PSMB5L3MBTL1ATMALOX5CYP11B1
SCHEMBL4549320 0.78 CYP11B1 (0.35) ALOX5CYP11B1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9406889-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-08-02 US disclosed
US-20150171333-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-18 US disclosed
US-8968888-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-03-03 US disclosed
US-20120104369-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120104369-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device MC1R, NR2E3, RPS19 PSMB5 2805/4885L3MBTL1 492/4885ATM 3847/4885
US-20150171333-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device MC1R, NR2E3, RPS19 PSMB5 2805/4885L3MBTL1 492/4885ATM 3847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.