SCHEMBL4549349

SCHEMBL4549349

CCC(C)c1ccc2cc(-c3ccc(-c4cccc5c4sc4ccccc45)cc3)c3ccccc3c2c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.45
PARP14 Q460N5 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.34
ATM Q13315 1/20 0.34
PRKDC P78527 3/20 0.34
TLR8 Q9NR97 1/20 0.32
TLR7 Q9NYK1 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
RAB9A P51151 1/20 0.32
MAPT P10636 1/20 0.32
MCL1 Q07820 1/20 0.31
S1PR4 O95977 4/20 0.31
S1PR5 Q9H228 3/20 0.31
HDAC4 P56524 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC8 Q9BY41 1/20 0.30
GRIA4 P48058 1/20 0.30
PIK3CD O00329 1/20 0.30
BRD4 O60885 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4549340 0.89 ALOX5 (0.49) ALOX5PARP14L3MBTL1ATMPRKDC
SCHEMBL4549314 0.82 MCL1 (0.33) ALOX5L3MBTL1ATMTLR8TLR7
SCHEMBL4549339 0.81 ALOX5 (0.49) ALOX5PARP14L3MBTL1ATMPRKDC
SCHEMBL4549348 0.81 ALOX5 (0.46) ALOX5PARP14L3MBTL1ATMPRKDC
SCHEMBL4549347 0.80 ALOX5 (0.52) ALOX5PARP14L3MBTL1ATMPRKDC
SCHEMBL4549350 0.80 ALOX5 (0.47) ALOX5PARP14L3MBTL1ATMPRKDC
SCHEMBL896331 0.79 ALOX5 (0.60) ALOX5PARP14L3MBTL1ATMPRKDC
SCHEMBL4549351 0.78 ALOX5 (0.53) ALOX5PARP14PRKDCKDM4EALDH1A1
SCHEMBL4549357 0.78 ALOX5 (0.57) ALOX5PARP14PRKDCKDM4EALDH1A1
SCHEMBL4549356 0.78 ALOX5 (0.53) ALOX5PARP14PRKDCKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9406889-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-08-02 US disclosed
US-9406889-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-08-02 US disclosed
US-20150171333-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-18 US disclosed
US-20150171333-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-18 US disclosed
US-8968888-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-03-03 US disclosed
US-8968888-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-03-03 US disclosed
US-20120104369-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-03 US disclosed
US-20120104369-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120104369-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device MC1R, NR2E3, RPS19 ALOX5 3393/4885PARP14 1234/4885L3MBTL1 492/4885
US-20150171333-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device MC1R, NR2E3, RPS19 ALOX5 3393/4885PARP14 1234/4885L3MBTL1 492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.