Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.67 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4549455 | 0.94 | NPC1 (0.58) | NPC1RAB9ANLRP3MAP4K4ALDH1A1 | |
| SCHEMBL19244899 | 0.84 | MAP4K4 (0.50) | NPC1RAB9ANLRP3MAP4K4ALDH1A1 | |
| SCHEMBL10775340 | 0.84 | NPC1 (0.77) | NPC1RAB9ANLRP3MAP4K4ALDH1A1 | |
| SCHEMBL1230233 | 0.81 | TLR2 (0.46) | NPC1RAB9ANLRP3MAP4K4ALDH1A1 | |
| SCHEMBL27544953 | 0.80 | NPC1 (0.71) | NPC1RAB9ANLRP3MAP4K4MEN1 | |
| SCHEMBL15034499 | 0.80 | NPC1 (0.71) | NPC1RAB9ANLRP3MAP4K4ALDH1A1 | |
| SCHEMBL27584245 | 0.80 | NPC1 (0.71) | NPC1RAB9ANLRP3MAP4K4MAPT | |
| SCHEMBL181896 | 0.79 | NPC1 (0.65) | NPC1RAB9ANLRP3MAP4K4ALDH1A1 | |
| SCHEMBL1230778 | 0.79 | NPC1 (0.43) | NPC1RAB9ANLRP3MAP4K4ALDH1A1 | |
| SCHEMBL28692512 | 0.78 | NPC1 (0.68) | NPC1RAB9ANLRP3MAP4K4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732109-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2017-08-15 | — | — | US | disclosed |
| US-9732109-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2017-08-15 | — | — | US | disclosed |
| US-9179681-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2015-11-10 | — | — | US | disclosed |
| US-9018363-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2015-04-28 | — | — | US | disclosed |
| US-9006468-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2015-04-14 | — | — | US | disclosed |
| US-20150080326-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2015-03-19 | — | — | US | disclosed |
| US-20140148340-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2014-05-29 | — | — | US | disclosed |
| US-8680269-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2014-03-25 | — | — | US | disclosed |
| US-20120172218-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-07-05 | — | — | US | disclosed |
| US-20120172217-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-07-05 | — | — | US | disclosed |
| US-20120122805-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-05-17 | — | — | US | disclosed |
| US-8178658-B2 | Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group | DOW AGROSCIENCES, LLC (US) | 2012-05-15 | — | — | US | disclosed |
| US-20090209476-A1 | Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group | DOW AGROSCIENCES LLC (US) | 2009-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209476-A1 | Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group | DDT, ACHE, NANP | NPC1 1008/4885RAB9A 371/4885NLRP3 246/4885 |
| US-20120172218-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PTMS | NPC1 4139/4885RAB9A 848/4885NLRP3 4491/4885 |
| US-20150080326-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PTMS | NPC1 4139/4885RAB9A 848/4885NLRP3 4491/4885 |
| US-20140148340-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PLCG2 | NPC1 3584/4885RAB9A 487/4885NLRP3 4114/4885 |
| US-20120172217-A1 | PESTICIDAL COMPOSITIONS | DDT, AADAC, ACHE | NPC1 1488/4885RAB9A 753/4885NLRP3 2368/4885 |
| US-20120122805-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PTMS | NPC1 4139/4885RAB9A 848/4885NLRP3 4491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.